Show simple item record

dc.creatorKukić, Jelena
dc.creatorDobrić, Silva
dc.creatorPetrović, Silvana
dc.date.accessioned2019-09-02T11:11:22Z
dc.date.available2019-09-02T11:11:22Z
dc.date.issued2007
dc.identifier.issn1388-0209
dc.identifier.urihttp://farfar.pharmacy.bg.ac.rs/handle/123456789/991
dc.description.abstractThis work investigates the anti- inflammatory activity of methanol extracts of four endemic Stachys ( Labiatae) taxa from the Balkans: S. beckeana Dorfler & Hayek, S. anisochila Vis. et Pancic, S. plumosa Griseb., and S. alpina L. subsp. dinarica Murb. As a model of acute inflammation, carrageenan- induced paw edema in rats was used. Extracts, applied at doses of 50, 100, and 200 mg/ kg p. o., exhibited dose- dependent activity. S. beckeana and S. anisochila extracts were the most active ones ( ED50 154.52 and 162.24 mg/ kg, respectively), with the activity comparable with indomethacin at doses of 2 and 4 mg/ kg. S. plumosa extract has shown less- pronounced anti- inflammatory effect ( ED50 220.81 mg= kg). Extract of S. alpina subsp. dinarica had the lowest efficiency, attenuating inflammation less than 50%.en
dc.publisherTaylor & Francis Ltd, Abingdon
dc.relationinfo:eu-repo/grantAgreement/MESTD/MPN2006-2010/143012/RS//
dc.rightsopenAccess
dc.sourcePharmaceutical Biology
dc.subjectanti-inflammatory activityen
dc.subjectdinaricaen
dc.subjectS. alpina subsp.en
dc.subjectS. beckeanaen
dc.subjectS. plumosaen
dc.subjectStachys anisochilaen
dc.titleInfluence of some Stachys taxa on carrageenan-induced paw edema in ratsen
dc.typearticle
dc.rights.licenseBY-NC
dcterms.abstractКукић, Јелена; Петровић, Силвана; Добрић, Силва;
dc.citation.volume45
dc.citation.issue7
dc.citation.spage560
dc.citation.epage563
dc.citation.other45(7): 560-563
dc.citation.rankM23
dc.identifier.wos000249795100006
dc.identifier.doi10.1080/13880200701498937
dc.identifier.scopus2-s2.0-34548361329
dc.identifier.fulltexthttp://farfar.pharmacy.bg.ac.rs//bitstream/id/2314/989.pdf
dc.identifier.rcubconv_1910
dc.type.versionpublishedVersion


Files in this item

Thumbnail

This item appears in the following Collection(s)

Show simple item record