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Influence of some Stachys taxa on carrageenan-induced paw edema in rats
dc.creator | Kukić, Jelena | |
dc.creator | Dobrić, Silva | |
dc.creator | Petrović, Silvana | |
dc.date.accessioned | 2019-09-02T11:11:22Z | |
dc.date.available | 2019-09-02T11:11:22Z | |
dc.date.issued | 2007 | |
dc.identifier.issn | 1388-0209 | |
dc.identifier.uri | https://farfar.pharmacy.bg.ac.rs/handle/123456789/991 | |
dc.description.abstract | This work investigates the anti- inflammatory activity of methanol extracts of four endemic Stachys ( Labiatae) taxa from the Balkans: S. beckeana Dorfler & Hayek, S. anisochila Vis. et Pancic, S. plumosa Griseb., and S. alpina L. subsp. dinarica Murb. As a model of acute inflammation, carrageenan- induced paw edema in rats was used. Extracts, applied at doses of 50, 100, and 200 mg/ kg p. o., exhibited dose- dependent activity. S. beckeana and S. anisochila extracts were the most active ones ( ED50 154.52 and 162.24 mg/ kg, respectively), with the activity comparable with indomethacin at doses of 2 and 4 mg/ kg. S. plumosa extract has shown less- pronounced anti- inflammatory effect ( ED50 220.81 mg= kg). Extract of S. alpina subsp. dinarica had the lowest efficiency, attenuating inflammation less than 50%. | en |
dc.publisher | Taylor & Francis Ltd, Abingdon | |
dc.relation | info:eu-repo/grantAgreement/MESTD/MPN2006-2010/143012/RS// | |
dc.rights | openAccess | |
dc.rights.uri | https://creativecommons.org/licenses/by-nc/4.0/ | |
dc.source | Pharmaceutical Biology | |
dc.subject | anti-inflammatory activity | en |
dc.subject | dinarica | en |
dc.subject | S. alpina subsp. | en |
dc.subject | S. beckeana | en |
dc.subject | S. plumosa | en |
dc.subject | Stachys anisochila | en |
dc.title | Influence of some Stachys taxa on carrageenan-induced paw edema in rats | en |
dc.type | article | |
dc.rights.license | BY-NC | |
dcterms.abstract | Кукић, Јелена; Петровић, Силвана; Добрић, Силва; | |
dc.citation.volume | 45 | |
dc.citation.issue | 7 | |
dc.citation.spage | 560 | |
dc.citation.epage | 563 | |
dc.citation.other | 45(7): 560-563 | |
dc.citation.rank | M23 | |
dc.identifier.wos | 000249795100006 | |
dc.identifier.doi | 10.1080/13880200701498937 | |
dc.identifier.scopus | 2-s2.0-34548361329 | |
dc.identifier.fulltext | https://farfar.pharmacy.bg.ac.rs//bitstream/id/2314/989.pdf | |
dc.type.version | publishedVersion |