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α6-Containing GABAA Receptors: Functional Roles and Therapeutic Potentials
(American Society for Pharmacology and Experimental Therapy, 2022)
GABAA receptors containing the α6 subunit are highly expressed in cerebellar granule cells and less abundantly in many other neuronal and peripheral tissues. Here, we for the first time summarize their importance for the ...
The cost-effectiveness analysis of coronary artery disease diagnostic parameters in a clinical laboratory setting
(Elsevier, 2007)
OBJECTIVES: The aim of this study was to analyse the cost-
effectiveness of consecutive supplementing of the Framingham
scoring (FRS) algorithm for coronary artery disease (CAD) risk
assessment with apolipoproteins B ...
Antiepileptic drugs as analgesics/adjuvants in inflammatory pain: current preclinical evidence
(Pergamon-Elsevier Science Ltd, Oxford, 2018)
Inflammatory pain is the most common type of pain that is treated clinically. The use of currently available treatments (classic analgesics - NSAID5, paracetamol and opioids) is limited by insufficient efficacy and/or side ...
Synthesis and biological properties of some new thiosemicarbazones
(Pergamon-Elsevier Science Ltd, Oxford, 2010)
Biological activity and chemical composition of different berry juices
(Elsevier Sci Ltd, Oxford, 2011)
Total phenolics total anthocyanins mineral content radical scavenging activity and antiproliferative activity against human cancer cell lines were evaluated in fresh pressed juices of five different berries Total phenolic ...
Study of chitosan/xanthan gum polyelectrolyte complexes formation, solid state and influence on ibuprofen release kinetics
(Elsevier B.V., 2020)
This study investigated the combined influence of pH adjusting agent type (hydrochloric, acetic or lactic acid) and initial pH value (3.6, 4.6, and 5.6) on formation of biocompatible chitosan/xanthan polyelectrolyte complexes ...
Association of acute Babesia canis infection and serum lipid, lipoprotein, and apoprotein concentrations in dogs
(Blackwell Publishing Inc., 2019)
Background: Babesia canis infection induces a marked acute phase response (APR) that might be associated with alteration in lipid and lipoprotein metabolism and disease prognosis. Hypothesis: Dogs with B. canis-induced APR ...
Design and Synthesis of Novel Deuterated Ligands Functionally Selective for the gamma-Aminobutyric Acid Type A Receptor (GABA(A)R) alpha 6 Subtype with Improved Metabolic Stability and Enhanced Bioavailability
(Amer Chemical Soc, Washington, 2018)
Recent reports indicate that alpha 6/beta 2/3 gamma 2 GABA(A)R selective ligands may be important for the treatment of trigeminal activation-related pain and neuropsychiatric disorders with sensori-motor gating deficits. ...
Synchronization of noisy delayed feedback systems with delayed coupling
(American Physical Soc, College Pk, 2007)
Synchronization of delayed coupled and stochastically perturbed systems with delayed nonlinear feedback is studied, using as an example circular chains of three and four delayed coupled Ikeda oscillators. It is proved that ...