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Toxicokinetics and correlation of carbamazepine salivary and serum concentrations in acute poisonings / Toksikokinetika i korelacija koncentracija karbamazepina u salivi i serumu kod akutnog trovanja
(Vojnomedicinska akademija - Institut za naučne informacije, Beograd, 2012)
Background/Aim. Saliva is a body fluid which, like serum, can be used for determination of concentrations of certain drugs, both in pharmacotherapy as well as in acute poisonings. The aim of this study was to determine ...
Biofilm formation of achromobacter xylosoxidans on contact lens
(Akademiai Kiado Rt, Budapest, 2017)
Achromobacter spp. may contaminate lenses, lens cases, and contact lens solutions and cause ocular infections. The aim of this study was to investigate the possibility of isolated strain of Achromobacter xylosoxidans to ...
The effect of β-cyclodextrin and pH on bifonazole hydrosolubility / Uticaj β-ciklodekstrina i PH na rastvorljivost bifonazola u vodi
(Srpsko hemijsko društvo, Beograd, 2004)
The equlibria of bifonazole in saturated water solution within the pH range 4 to 10 [I = 0.1 mol/dm3 (NaCl); 25 ºC] were studied spectrophotometrically. Based on the equlibrium constants determined in a heterogeneous system, ...
The physicochemical characterization and in vitro/in vivo evaluation of natural surfactants-based emulsions as vehicles for diclofenac diethylamine
(Taylor & Francis Ltd, Abingdon, 2007)
Two sugar-based emulsifiers, cetearyl alcohol & cetearyl glycoside and sorbitan stearate & sucrose cocoate, known as potential promoters of lamellar liquid crystals/gel phases, were investigated in order to formulate an ...
Docking studies and anti-inflammatory activity of ss-Hydroxy-ss-arylpropanoic acids
(Molecular Diversity Preservation Int, Basel, 2008)
The article describes a two-step synthesis of diastereomeric 3-hydroxy-2methyl-3-( 4-biphenylyl) butanoic acids. In the first step an intermediate alpha-bromo propanoic acid 1-ethoxyethyl ester was synthesized. The second ...
Generalized regression neural networks in prediction of drug stability
(Pharmaceutical Press-Royal Pharmaceutical Soc Great Britian, London, 2007)
This study had two aims. Firstly, we wanted to model the effects of the percentage of Eudragit RS PO and compression pressure as the most important process and formulation variables on the time course of drug release from ...
Simultaneous Determination of Maprotiline, Desipramine, and Moclobemide by Reversed-Phase High-Performance Liquid Chromatography and Statistical Optimization
(Taylor & Francis Inc, Philadelphia, 2009)
A method for separation of three antidepressants, maprotiline, desipramine, and moclobemide, by reversed-phase high-performance liquid chromatography (RP-HPLC) was developed and validated. To find optimal conditions and ...
Effects of zinc on the mineralization of bone nodules from human osteoblast-like cells
(Humana Press Inc, Totowa, 2007)
Zinc is an important mineral that is required for normal bone development. However, the direct effects of zinc on the mineralization of bone cells of human origin are not clear. The objective of this study was to determine ...
Validation of an analytical procedure for simultaneous determination of hydrochlorothiazide, lisinopril, and their impurities
(Univ Silesia, Inst Chemistry, Katowice, 2007)
The main objective of the work discussed in this paper was evaluation of a chromatographic method for simultaneous determination of hydrochlorothiazide (HCTZ), lisinopril (L), and their impurities in pharmaceuticals. ...