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The antioxidant role of ferritin and transferrin in elite athletes
(Nova Science Publishers, Inc., 2012)
Physical activity has been shown to increase the production of free radicals to a point that can exceed internal protective antioxidant system. The harmful effects of free radicals are neutralized by activity of antioxidant ...
Abyssomicins: Isolation, properties, and synthesis
(Elsevier B.V., 2013)
The discovery of abyssomicin class of natural products has been the outcome of the search for secondary metabolites possessing inhibitory effect on p-aminobenzoic (pABA) acid biosynthesis, a biosynthetic pathway found in ...
Robustness of liquid chromatographic method: How to achieve it and how to confirm it?
(Nova Science Publishers, Inc., 2013)
The quality of liquid chromatographic methods developed for pharmaceutical applications is strongly dependent on their robustness. The robustness issue requires a studious strategy where many important aspects regarding ...
Modified Natural Zeolites-Functional Characterization and Biomedical Application
(Wiley Blackwell, 2014)
Natural and synthetic zeolites have emerged as potential materials for biomedical application in recent years. Zeolites are hydrated microporous tektoaluminosilicates consisting of three-dimensional frameworks of SiO4 and ...
Objective skin performance evaluation: How mild are APGs to the skin?
(Elsevier Inc., 2014)
Emulsion systems are the most common vehicles for topical drugs/cosmetic actives. Absence of skin irritation potential is an important legislative requirement. Overcoming emulsion irritancy is usually achieved by selection ...
Quality-by-design in pharmaceutical development
(Elsevier Inc., 2013)
This first chapter introduces the concept of quality-by-design (QbD) and its role in pharmaceutical product development. QbD assures the quality of a pharmaceutical product through scientific development and risk management ...
Clinical pharmacokinetic characteristics of novel antiepileptic drugs
(Nova Science Publishers, Inc., 2012)
The choice of an antiepileptic drug (AED) is usually based upon the epileptic seizure type. However, pharmacokinetic (PK) characteristics of AEDs may be valuable support in choosing the optimal therapeutic option for the ...
Computer-aided formulation development
(Elsevier Inc., 2013)
This chapter introduces the concept of formulation development assisted by computer applications. Development and optimization of various types of pharmaceutical emulsions microemulsions, self-microemulsifying systems, and ...
Chemometric methods application in pharmaceutical products processes analysis control
(Elsevier Inc., 2013)
This chapter provides a basic theoretical background on chemometrics and chemometric methods for the analysis of multivariate data. Multivariate data analysis is essential for both product and process development and ...
Artificial neural networks in the optimization of microemulsion liquid chromatography retention and resolution
(Nova Science Publishers, Inc., 2011)
Artificial neural networks (ANNs) present a powerful tool for the modeling of chromatographic retention and resolution as they provide the ability to predict the effects of changes in chosen chromatographic parameters under ...