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Protective effect of dry olive leaf extract in adrenaline induced DNA damage evaluated using in vitro comet assay with human peripheral leukocytes
(Pergamon-Elsevier Science Ltd, Oxford, 2014)
Excessive release of stress hormone adrenaline is accompanied by generation of reactive oxygen species which may cause disruption of DNA integrity leading to cancer and age-related disorders. Phenolic-rich plant product ...
The impact of prolonged cadmium exposure and co-exposure with polychlorinated biphenyls on thyroid function in rats
(Elsevier Ireland Ltd, Clare, 2013)
Endocrine-disrupting chemicals currently represent one of the major concerns and this study was aimed to investigate the effects of different doses of cadmium, widespread toxic metal, on the levels of thyroid hormones and ...
Evaluation of cytogenetic and DNA damage in human lymphocytes treated with adrenaline in vitro
(Pergamon-Elsevier Science Ltd, Oxford, 2015)
Catechol groups can be involved in redox cycling accompanied by generation of reactive oxygen species (ROS) which may lead to oxidative damage of cellular macromolecules including DNA. The objective of this investigation ...
Modification of the rate of aging of diisopropylfluorophosphate-inhibited neuropathy target esterase of hen brain
(Elsevier Sci Ireland Ltd, Clare, 1998)
This study was aimed to investigate the possibility of modifying the rate of aging of diisopropylfluorophosphate-inhibited neuropathy target esterase (NTE) of hen blain. This reaction on NTE occurs with a half-time of 7.4 ...
Derivation of benchmark doses for male reproductive toxicity in a subacute low-level Pb exposure model in rats
(Elsevier Ireland Ltd, 2023)
The objectives of the study were to simulate low-level Pb exposure scenario in an animal model and to examine reproductive adverse effects. Based on obtained data, we have performed Benchmark dose (BMD)-response modelling. ...