Cytotoxicity and antimicrobial activity of Teucrium scordium L. (Lamiaceae) extracts
Аутори
Kundaković, TatjanaMilenković, Marina
Topić, Aleksandra
Stanojković, Tatjana
Juranić, Zorica
Lakušić, Branislava
Чланак у часопису (Објављена верзија)
Метаподаци
Приказ свих података о документуАпстракт
Cytotoxicity and antimicrobial activity of cyclohexane, dichlormethane and methanol extracts of Teucrium scordium subspec. scordioides was studied. Cyclohexane and dichlormethane extracts of T. scordium possessed high citotoxicity against MDA-MB-361 cells (IC(50)=130.33+/-0.1 mu g/ml and IC(50)=189.89+/-3.99 mu g/ml, respectively). Dichlormethane extract was more effective against MDA-MB-453 cell line (IC(50)=130.33 +/- 0.1 mu g/ml). The methanol extract of T. scordium possessed no cytotoxicity against breast cancer cell lines, MDA-MB-361 and MDA-MB-453. Herb extracts of T. scordium have shown weak antibacterial activity on Pseudomonas aeruginosa, Klebsiella pneumoniae, Escherichia coli and Bacillus subtilis with no activity against Staphylococcus aureus, S. epidermidis, Micrococcus luteus, Enterococcus faecalis, and Candida albicans.
Кључне речи:
Teucrium scordium subsp scordioides / cytotoxicity / antimicrobial activityИзвор:
African Journal of Microbiology Research, 2011, 5, 19, 2950-2954Издавач:
- Academic Journals, Victoria Island
Финансирање / пројекти:
- Испитивање лековитог потенцијала биљака: морфолошка, хемијска и фармаколошка карактеризација (RS-MESTD-Basic Research (BR or ON)-173021)
Институција/група
PharmacyTY - JOUR AU - Kundaković, Tatjana AU - Milenković, Marina AU - Topić, Aleksandra AU - Stanojković, Tatjana AU - Juranić, Zorica AU - Lakušić, Branislava PY - 2011 UR - https://farfar.pharmacy.bg.ac.rs/handle/123456789/1489 AB - Cytotoxicity and antimicrobial activity of cyclohexane, dichlormethane and methanol extracts of Teucrium scordium subspec. scordioides was studied. Cyclohexane and dichlormethane extracts of T. scordium possessed high citotoxicity against MDA-MB-361 cells (IC(50)=130.33+/-0.1 mu g/ml and IC(50)=189.89+/-3.99 mu g/ml, respectively). Dichlormethane extract was more effective against MDA-MB-453 cell line (IC(50)=130.33 +/- 0.1 mu g/ml). The methanol extract of T. scordium possessed no cytotoxicity against breast cancer cell lines, MDA-MB-361 and MDA-MB-453. Herb extracts of T. scordium have shown weak antibacterial activity on Pseudomonas aeruginosa, Klebsiella pneumoniae, Escherichia coli and Bacillus subtilis with no activity against Staphylococcus aureus, S. epidermidis, Micrococcus luteus, Enterococcus faecalis, and Candida albicans. PB - Academic Journals, Victoria Island T2 - African Journal of Microbiology Research T1 - Cytotoxicity and antimicrobial activity of Teucrium scordium L. (Lamiaceae) extracts VL - 5 IS - 19 SP - 2950 EP - 2954 UR - https://hdl.handle.net/21.15107/rcub_farfar_1489 ER -
@article{ author = "Kundaković, Tatjana and Milenković, Marina and Topić, Aleksandra and Stanojković, Tatjana and Juranić, Zorica and Lakušić, Branislava", year = "2011", abstract = "Cytotoxicity and antimicrobial activity of cyclohexane, dichlormethane and methanol extracts of Teucrium scordium subspec. scordioides was studied. Cyclohexane and dichlormethane extracts of T. scordium possessed high citotoxicity against MDA-MB-361 cells (IC(50)=130.33+/-0.1 mu g/ml and IC(50)=189.89+/-3.99 mu g/ml, respectively). Dichlormethane extract was more effective against MDA-MB-453 cell line (IC(50)=130.33 +/- 0.1 mu g/ml). The methanol extract of T. scordium possessed no cytotoxicity against breast cancer cell lines, MDA-MB-361 and MDA-MB-453. Herb extracts of T. scordium have shown weak antibacterial activity on Pseudomonas aeruginosa, Klebsiella pneumoniae, Escherichia coli and Bacillus subtilis with no activity against Staphylococcus aureus, S. epidermidis, Micrococcus luteus, Enterococcus faecalis, and Candida albicans.", publisher = "Academic Journals, Victoria Island", journal = "African Journal of Microbiology Research", title = "Cytotoxicity and antimicrobial activity of Teucrium scordium L. (Lamiaceae) extracts", volume = "5", number = "19", pages = "2950-2954", url = "https://hdl.handle.net/21.15107/rcub_farfar_1489" }
Kundaković, T., Milenković, M., Topić, A., Stanojković, T., Juranić, Z.,& Lakušić, B.. (2011). Cytotoxicity and antimicrobial activity of Teucrium scordium L. (Lamiaceae) extracts. in African Journal of Microbiology Research Academic Journals, Victoria Island., 5(19), 2950-2954. https://hdl.handle.net/21.15107/rcub_farfar_1489
Kundaković T, Milenković M, Topić A, Stanojković T, Juranić Z, Lakušić B. Cytotoxicity and antimicrobial activity of Teucrium scordium L. (Lamiaceae) extracts. in African Journal of Microbiology Research. 2011;5(19):2950-2954. https://hdl.handle.net/21.15107/rcub_farfar_1489 .
Kundaković, Tatjana, Milenković, Marina, Topić, Aleksandra, Stanojković, Tatjana, Juranić, Zorica, Lakušić, Branislava, "Cytotoxicity and antimicrobial activity of Teucrium scordium L. (Lamiaceae) extracts" in African Journal of Microbiology Research, 5, no. 19 (2011):2950-2954, https://hdl.handle.net/21.15107/rcub_farfar_1489 .