An alkyl polyglucoside-mixed emulsifier as stabilizer of emulsion systems: The influence of colloidal structure on emulsions skin hydration potential
Само за регистроване кориснике
2011
Аутори
Savić, SnežanaLukić, Milica
Pantelić, Ivana
Reichl, Stephan
Tamburić, Slobodanka
Mueller-Goymann, Christel
Чланак у часопису (Објављена верзија)
Метаподаци
Приказ свих података о документуАпстракт
To be considered as a suitable vehicle for drugs/cosmetic actives, an emulsion system should have a number of desirable properties mainly dependent on surfactant used for its stabilization. In the current study, C12-14 alkyl polyglucoside (APG)-mixed emulsifier of natural origin has been investigated in a series of binary (emulsifier concentration 10-25% (w/w)) and ternary systems with fixed emulsifier content (15% (w/w)) with or without glycerol. To elucidate the systems' colloidal structure the following physicochemical techniques were employed: polarization and transmission electron microscopy, X-ray diffraction (WAXD and SAXD), thermal analysis (DSC and TGA), complex rheological, pH, and conductivity measurements. Additionally, the emulsion vehicles' skin hydration potential was tested in vivo, on human skin under occlusion. In a series of binary systems with fixed emulsifier/water ratios ranging from 10/90 to 25/75 the predominance of a lamellar mesophase was found, changing its c...haracter from a liquid crystalline to a gel crystalline type. The same was observed in gel emulsions containing equal amounts of emulsifier and oil (15% (w/w)), but varying in glycerol content (0-25%). Different emulsion samples exhibited different water distribution modes in the structure, reflecting their rheological behavior and also their skin hydration capacity.
Кључне речи:
Alkyl polyglucoside-mixed emulsifier / Lamellar mesophase / Water distribution / Rheological behavior / Skin hydrationИзвор:
Journal of Colloid and Interface Science, 2011, 358, 1, 182-191Издавач:
- Academic Press Inc Elsevier Science, San Diego
Финансирање / пројекти:
- Развој микро- и наносистема као носача за лекове са антиинфламаторним деловањем и метода за њихову карактеризацију (RS-MESTD-Technological Development (TD or TR)-34031)
DOI: 10.1016/j.jcis.2011.02.049
ISSN: 0021-9797
PubMed: 21421214
WoS: 000289600300025
Scopus: 2-s2.0-79953300461
Институција/група
PharmacyTY - JOUR AU - Savić, Snežana AU - Lukić, Milica AU - Pantelić, Ivana AU - Reichl, Stephan AU - Tamburić, Slobodanka AU - Mueller-Goymann, Christel PY - 2011 UR - https://farfar.pharmacy.bg.ac.rs/handle/123456789/1533 AB - To be considered as a suitable vehicle for drugs/cosmetic actives, an emulsion system should have a number of desirable properties mainly dependent on surfactant used for its stabilization. In the current study, C12-14 alkyl polyglucoside (APG)-mixed emulsifier of natural origin has been investigated in a series of binary (emulsifier concentration 10-25% (w/w)) and ternary systems with fixed emulsifier content (15% (w/w)) with or without glycerol. To elucidate the systems' colloidal structure the following physicochemical techniques were employed: polarization and transmission electron microscopy, X-ray diffraction (WAXD and SAXD), thermal analysis (DSC and TGA), complex rheological, pH, and conductivity measurements. Additionally, the emulsion vehicles' skin hydration potential was tested in vivo, on human skin under occlusion. In a series of binary systems with fixed emulsifier/water ratios ranging from 10/90 to 25/75 the predominance of a lamellar mesophase was found, changing its character from a liquid crystalline to a gel crystalline type. The same was observed in gel emulsions containing equal amounts of emulsifier and oil (15% (w/w)), but varying in glycerol content (0-25%). Different emulsion samples exhibited different water distribution modes in the structure, reflecting their rheological behavior and also their skin hydration capacity. PB - Academic Press Inc Elsevier Science, San Diego T2 - Journal of Colloid and Interface Science T1 - An alkyl polyglucoside-mixed emulsifier as stabilizer of emulsion systems: The influence of colloidal structure on emulsions skin hydration potential VL - 358 IS - 1 SP - 182 EP - 191 DO - 10.1016/j.jcis.2011.02.049 ER -
@article{ author = "Savić, Snežana and Lukić, Milica and Pantelić, Ivana and Reichl, Stephan and Tamburić, Slobodanka and Mueller-Goymann, Christel", year = "2011", abstract = "To be considered as a suitable vehicle for drugs/cosmetic actives, an emulsion system should have a number of desirable properties mainly dependent on surfactant used for its stabilization. In the current study, C12-14 alkyl polyglucoside (APG)-mixed emulsifier of natural origin has been investigated in a series of binary (emulsifier concentration 10-25% (w/w)) and ternary systems with fixed emulsifier content (15% (w/w)) with or without glycerol. To elucidate the systems' colloidal structure the following physicochemical techniques were employed: polarization and transmission electron microscopy, X-ray diffraction (WAXD and SAXD), thermal analysis (DSC and TGA), complex rheological, pH, and conductivity measurements. Additionally, the emulsion vehicles' skin hydration potential was tested in vivo, on human skin under occlusion. In a series of binary systems with fixed emulsifier/water ratios ranging from 10/90 to 25/75 the predominance of a lamellar mesophase was found, changing its character from a liquid crystalline to a gel crystalline type. The same was observed in gel emulsions containing equal amounts of emulsifier and oil (15% (w/w)), but varying in glycerol content (0-25%). Different emulsion samples exhibited different water distribution modes in the structure, reflecting their rheological behavior and also their skin hydration capacity.", publisher = "Academic Press Inc Elsevier Science, San Diego", journal = "Journal of Colloid and Interface Science", title = "An alkyl polyglucoside-mixed emulsifier as stabilizer of emulsion systems: The influence of colloidal structure on emulsions skin hydration potential", volume = "358", number = "1", pages = "182-191", doi = "10.1016/j.jcis.2011.02.049" }
Savić, S., Lukić, M., Pantelić, I., Reichl, S., Tamburić, S.,& Mueller-Goymann, C.. (2011). An alkyl polyglucoside-mixed emulsifier as stabilizer of emulsion systems: The influence of colloidal structure on emulsions skin hydration potential. in Journal of Colloid and Interface Science Academic Press Inc Elsevier Science, San Diego., 358(1), 182-191. https://doi.org/10.1016/j.jcis.2011.02.049
Savić S, Lukić M, Pantelić I, Reichl S, Tamburić S, Mueller-Goymann C. An alkyl polyglucoside-mixed emulsifier as stabilizer of emulsion systems: The influence of colloidal structure on emulsions skin hydration potential. in Journal of Colloid and Interface Science. 2011;358(1):182-191. doi:10.1016/j.jcis.2011.02.049 .
Savić, Snežana, Lukić, Milica, Pantelić, Ivana, Reichl, Stephan, Tamburić, Slobodanka, Mueller-Goymann, Christel, "An alkyl polyglucoside-mixed emulsifier as stabilizer of emulsion systems: The influence of colloidal structure on emulsions skin hydration potential" in Journal of Colloid and Interface Science, 358, no. 1 (2011):182-191, https://doi.org/10.1016/j.jcis.2011.02.049 . .