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Quality-by-design in pharmaceutical development
(Elsevier Inc., 2013)
This first chapter introduces the concept of quality-by-design (QbD) and its role in pharmaceutical product development. QbD assures the quality of a pharmaceutical product through scientific development and risk management ...
The Impact of Urea on the Colloidal Structure of Alkylpolyglucoside-Based Emulsions: Physicochemical and In Vitro In Vivo Characterization
(Wiley-VCH Verlag GMBH, Weinheim, 2011)
Modified Natural Zeolites-Functional Characterization and Biomedical Application
(Wiley Blackwell, 2014)
Natural and synthetic zeolites have emerged as potential materials for biomedical application in recent years. Zeolites are hydrated microporous tektoaluminosilicates consisting of three-dimensional frameworks of SiO4 and ...
Objective skin performance evaluation: How mild are APGs to the skin?
(Elsevier Inc., 2014)
Emulsion systems are the most common vehicles for topical drugs/cosmetic actives. Absence of skin irritation potential is an important legislative requirement. Overcoming emulsion irritancy is usually achieved by selection ...
Abyssomicins: Isolation, properties, and synthesis
(Elsevier B.V., 2013)
The discovery of abyssomicin class of natural products has been the outcome of the search for secondary metabolites possessing inhibitory effect on p-aminobenzoic (pABA) acid biosynthesis, a biosynthetic pathway found in ...
Polymeric Microparticles and Inorganic Micro/Nanoparticulate Drug Carriers: An Overview and Pharmaceutical Application
(Elsevier Inc., 2017)
Recent expansion of innovative micro- and nanosized drug carriers has been driven by utilization of materials with improved functional properties, along with employment of innovative preparation techniques. Various materials ...
Epidemiological Studies of Anticholinesterase Pesticide Poisoning in Serbia
(John Wiley and Sons, 2011)
Percutaneous penetration enhancement potential of microemulsion-based organogels
(Springer Berlin Heidelberg, 2016)
The skin, and particularly the most outer layer stratum corneum, is an effective barrier for molecules administered by conventional topical formulations (i.e., ointments, creams, hydrogels). Therefore, vehicles and carriers ...
Alkyl Polyglucoside-based delivery systems: In vitro/in vivo skin absorption assessment
(Elsevier Inc., 2014)
Skin permeation and penetration assessment is important not only for determining efficacy of a topical product, but also when comparing different formulations during development. This chapter reviews methods for dermal ...
Influence of Polycation Functional Properties on Polyanion Micro/Nanoparticles for NSAIDs Reinforced via Polyelectrolyte Complexation: Alginate-Chitosan Case Study
(Elsevier Inc., 2017)
In the last 2 decades, numerous studies have been carried out to synthesize biodegradable and nontoxic micro- and nanoparticulate carriers for nonsteroidal anti-inflammatory drugs. The potential benefits of these carriers ...