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Now showing items 31-40 of 206
3d printed buccal films for prolonged-release of propranolol hydrochloride: Development, characterization and bioavailability prediction
(MDPI, 2021)
Gelatin-polyvinylpyrrolidone (PVP) and gelatin-poly(vinyl alcohol) (PVA) mucoadhesive buccal films loaded with propranolol hydrochloride (PRH) were prepared by semi-solid extrusion 3D printing. The aim of this study was ...
Telepharmacy service experience during the COVID-19 pandemic in the Republic of Srpska, Bosnia and Herzegovina
(John Wiley and Sons Inc, 2022)
The COVID-19 pandemic exerted a profound impact on health systems worldwide. Moreover, significant concerns were raised in terms of middle- and long-term consequences of postponing care in non-COVID patients. The primary ...
Influence of Higenamine on Exercise Performance of Recreational Female Athletes: A Randomized Double-Blinded Placebo-Controlled Trial
(Frontiers Media S.A., 2021)
The aim of this study was to determine the ergogenic effects and the safety profile of a one-component higenamine supplement in female recreational athletes. Twelve recreational female basketball players (age 29–41 years, ...
MFI, BEA and FAU zeolite scavenging role in neonicotinoids and radical species elimination
(The Royal Society of Chemistry, 2022)
Ecotoxicity caused by neonicotinoid pesticides is largely due to oxidative stress on non-target species. Due to the fact that reactive radical species reach the environment, materials intended for pesticide removal should ...
Can non-cholesterol sterols indicate the presence of specific dysregulation of cholesterol metabolism in patients with colorectal cancer?
(Elsevier Inc., 2022)
Colorectal cancer (CRC) is a highly prevalent malignancy. Previous studies suggested that cholesterol might play a signficant role in malignant transformation and proliferation. Non-cholesterol sterols (NCS), which are ...
Development of lipid-based gastroretentive delivery system for gentian extract by double emulsion–melt dispersion technique
(MDPI, 2021)
Gentian (Gentiana lutea L., Gentianaceae) root extract (GRE) is used for the treatment of gastrointestinal disorders. However, its bioactive potential is limited in conventional forms due to the low bioavailability and ...
Modification of Keggin anion structure with ion beams—A new spectroscopic insights into the effects of keV- and MeV-ion beam irradiation on 12-tungstophosphoric acid
(John Wiley and Sons Ltd, 2022)
Ion beam irradiation is a versatile tool for structural modification andengineering of new materials. In this study, 12-tungstophosphoric acid (WPA)films of different thickness were spin-coated on platinized silicon substrate ...
Antiallergic Treatment of Bariatric Patients: Potentially Hampered Solubility/Dissolution and Bioavailability of Loratadine, but Not Desloratadine, Post-Bariatric Surgery
(American Chemical Society, 2022)
Gastrointestinal anatomical/physiological changes after bariatric surgery influence variables affecting the fate of drugs after ingestion, and medication management of these patients requires a thorough and complex mechanistic ...
The impact of treatment choices on potential drug–drug interactions in hypertensive patients
(John Wiley and Sons Inc, 2021)
Aims: The aim of this study was to analyse potential drug–drug interactions (pDDIs) and their potential adverse drug reactions (ADRs) among hypertensive patients. Moreover, we investigated the possibility of reducing pDDIs ...
Hepatocyte Thorns, A Novel Drug-Induced Stress Response in Human and Mouse Liver Spheroids
(MDPI, 2022)
The in vivo-relevant phenotype of 3D liver spheroids allows for long-term studies of, e.g., novel mechanisms of chronic drug-induced liver toxicity. Using this system, we present a novel drug-induced stress response in ...