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Приказ резултата 31-40 од 243
A Review of the Updated Pharmacophore for the Alpha 5 GABA(A) Benzodiazepine Receptor Model
(Hindawi Ltd, London, 2015)
An updated model of the GABA(A) benzodiazepine receptor pharmacophore of the alpha 5-BzR/GABA(A) subtype has been constructed prompted by the synthesis of subtype selective ligands in light of the recent developments in ...
Negative modulation of alpha(5) GABA(A) receptors in rats may partially prevent memory impairment induced by MK-801, but not amphetamine- or MK-801-elicited hyperlocomotion
(Sage Publications Ltd, London, 2015)
Reportedly, negative modulation of alpha(5) GABA(A) receptors may improve cognition in normal and pharmacologically-impaired animals, and such modulation has been proposed as an avenue for treatment of cognitive symptoms ...
Antioxidant and antimicrobial activity of a new generation phyto-gel / Antioksidativna i antimikrobna aktivnost fitogela novije generacije
(Univerzitet u Nišu - Tehnološki fakultet, Leskovac, 2015)
Antioxidant and antimicrobial activities of a new phyto-gel were studied in this work. The formulated gel is composed of propilene glycol extracts of St. John's worth (H. perforatum L.), comfrey (S. officinale L.), yarrow ...
The effect of the molecular properties of calcium channel blockers on their elimination route
(Srpsko biološko društvo, Beograd, i dr., 2015)
Calcium channel blockers (CCBs) are among the most widely used drugs in cardiovascular medicine. In this study, nine CCBs (amlodipine, felodipine, isradipine, nicardipine, nifedipine, nimodipine, nisoldipine, verapamil and ...
Diagnostic Value of Matrix Metalloproteinase-9 and Tissue Inhibitor of Matrix Metalloproteinase-1 in Sepsis-Associated Acute Kidney Injury
(Tohoku Univ Medical Press, Sendai, 2015)
Sepsis-associated acute kidney injury (SA-AKI) severely impacts morbidity and mortality in surgical patients with sepsis. Matrix metalloproteinase-9 (MMP-9) and tissue inhibitor of matrix rnetalloproteinase-1 (TIMP-1) have ...
Evaluation of Angiotensin-Converting Enzyme Inhibitor's Absorption with Retention Data of Micellar Thin-Layer Chromatography and Suitable Molecular Descriptor
(Oxford Univ Press Inc, Cary, 2015)
Twelve angiotensin-converting enzyme (ACE) inhibitors were studied to evaluate correlation between their absorption (ABS) data available in the literature (22-96%) and hydrophobicity parameters (k(m) and P-m/w) obtained ...
Comparison of drug release and mechanical properties of tramadol hydrochloride matrix tablets prepared with selected hydrophilic polymers / Poređenje oslobađanja tramadol-hidrohlorida i mehaničkih karakteristika matriks tableta izrađenih sa odabranim hidrofilnim polimerima
(Savez hemijskih inženjera, Beograd, 2015)
This study investigates the use of high molecular weight hydrophilic polymers, hypromellose and hydroxypropylcellulose, for the preparation of sustained release matrix tablets containing a high-dose highly soluble drug, ...
Optimization of technological procedure for amygdalin isolation from plum seeds (Pruni domesticae semen)
(Frontiers Media Sa, Lausanne, 2015)
The process of amygdalin extraction from plum seeds was optimized using central composite design (CCD) and multilayer perceptron (MLP). The effect of time, ethanol concentration, solid-to-liquid ratio, and temperature on ...
Assessment of the socio-economic impact of the chemicals environmental contamination
(Visoka škola za poslovnu ekonomiju i preduzetništvo, Beograd, 2015)
Socio-economic impact analysis is one of the key components of the complex management process in which risks from environmental contamination by chemicals are identifying and assessing. Paradigm of risk assessment covers ...
Massage-like stroking boosts the immune system in mice
(Nature Publishing Group, London, 2015)
Recent clinical evidence suggests that the therapeutic effect of massage involves the immune system and that this can be exploited as an adjunct therapy together with standard drug-based approaches. In this study, we ...