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Analysis of fluidized bed granulation process using conventional and novel modeling techniques
(Elsevier Science BV, Amsterdam, 2011)
Various modeling techniques have been applied to analyze fluidized-bed granulation process. Influence of various input parameters (product, inlet and outlet air temperature, consumption of liquid-binder, granulation ...
Fludized hot melt granulation: in situ vs. Spray-on procedure
(Elsevier Science BV, Amsterdam, 2011)
Characteristics of low-density and high-density lipoprotein subclasses in pediatric renal transplant recipients
(Elsevier Science BV, Amsterdam, 2011)
A comparison of two RNA isolation methods to determine sod1 and sod2 gene expression in human blood and mononuclear cells
(Elsevier Science BV, Amsterdam, 2011)
Population pharmacokinetics of topiramate in adult patients with epilepsy using nonlinear mixed effects modelling
(Elsevier Science BV, Amsterdam, 2013)
The objective of the study was to develop population pharmacokinetic model of topiramate (TPM) using nonlinear mixed effects modelling approach. Data were collected from 78 adult epileptic patients on mono- or co-therapy ...
Statistical and machine learning tools in evaluation and optimization of modified release products
(Elsevier Science BV, Amsterdam, 2011)
Application of gastrointestinal simulation for development of in vitro-in vivo correlation for levothyroxine sodium immediate-release tablets
(Elsevier Science BV, Amsterdam, 2011)
Coupled in silico platform: Computational fluid dynamics (CFD) and physiologically-based pharmacokinetic (PBPK) modelling
(Elsevier Science BV, Amsterdam, 2018)
One of the critical components of the respiratory drug delivery is the manner in which the inhaled aerosol is deposited in respiratory tract compartments. Depending on formulation properties, device characteristics and ...
Formulation of hydrogel-thickened nonionic microemulsions with enhanced percutaneous delivery of ibuprofen assessed in vivo in rats
(Elsevier Science BV, Amsterdam, 2016)
The study investigated usage of hydrogel of an anionic polymer xanthan gum for design of ibuprofen-loaded hydrogel-thickened microemulsions (HTMs) from the nonionic oil-in-water microemulsion (M). Xanthan gum demonstrated ...
Synthesis of the vitamin E amino acid esters with an enhanced anticancer activity and in silico screening for new antineoplastic drugs
(Elsevier Science BV, Amsterdam, 2016)
Tocopherols and tocotrienols belong to the family of vitamin E (VE) with the well-known antioxidant properties. For certain alpha-tocopherol and gamma-tocotrienol derivatives used as the lead compounds in this study, ...