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Determination of all pK(a) values of some di- and tri-carboxylic unsaturated and epoxy acids and their polylinear correlation with the carboxylic group atomic charges
(Scientific Reviews Ltd., 2003)
For a series of seven unsaturated and seven epoxy di- and tricarboxylic acids, pK(a)(a) values were determined potentiometrically in aqueous media at 25 degreesC and an ionic strength of 0.1 M (NaCl). The thermodynamic ...
Evaluation of global haemostatic assays and fibrin structure in patients with pre-eclampsia
(Wiley-Blackwell, 2020)
Introduction: Haemostatic balance shifted towards hypercoagulability in normal pregnancy is even more pronounced in pre-eclampsia (P-EC). The aim of this study was to analyse haemostatic disturbances and fibrin clot ...
Effect of small changes in natural origin-based emulsion systems on hydrocortisone skin absorption and performance: a comparison of two in vivo methods
(Taylor & Francis Ltd, Abingdon, 2014)
Context: Alkyl polyglucoside surfactants (APG) remain prominent natural origin stabilizers offering a prospect of combining satisfactory stability with mild dermatological properties and complete biodegradability. Objective: ...
Polymer-stabilized emulsion systems: Structural characteristics and physical stability evaluation
(Taylor & Francis Ltd, Abingdon, 2003)
In the course of investigation of the effects of polymeric emulsifier (Simulgel(R)A) on the structural characteristics and physical stability (during storage time) of semisolid o/w emulsion systems with different emulsifier ...
Quantitative analysis of nimesulide in plasma by thin-layer chromatography: Application to pharmacokinetic studies in man
(Research Inst Medicinal Plants, Budakalasz, 2003)
A thin-layer chromatographic (TLC) method for quantitative analysis of nimesulide in human plasma has been developed, validated, and applied to a pharmacokinetic study of healthy volunteers. A previously published method ...
Antioxidant status of patients with acute myocardial infarction
(Dustri-Verlag Dr Karl Feistle, Oberhaching, 2003)
Objectives: It has been suggested that dietary selenium (Se) deficiency is implicated in the etiology of cardiovascular disease. In this study, we examined the antioxidant status of patients with acute myocardial infarction ...
Potential drug–drug interactions associated with clinical and laboratory findings at hospital admission
(Springer, 2020)
Background Drug–drug interactions represent one of the causes of adverse therapy outcomes through deteriorated efficacy or safety. However, the true extent of harm related to drug–drug interactions is not well established ...
Potential Influence of Tubular Dysfunction on the Difference Between Estimated and Measured Glomerular Filtration Rate After Kidney Transplantation
(Elsevier Science Inc, New York, 2013)
Purpose. Because no consensus exists regarding the most accurate calculation to estimate glomerular filtration rate (GFR) based on serum creatinine concentrations (sCr) after kidney transplantation, this study sought to ...
Determination of carvedilol and its impurities in pharmaceuticals
(Vieweg, Wiesbaden, 2005)
A reversed-phase high-performance liquid chromatographic (RP-HPLC) method has been developed for separation of carvedilol and its impurities from Karvileks tablets. The best separation was achieved on a 100 mm x 4.6 mm, 5 ...
Biomarkers for Major Depressive Disorder: Economic Considerations
(Wiley, Hoboken, 2016)
Major depressive disorder (MDD) is a major psychiatric illness and it is predicted to be the second leading cause of disability by 2020 with a lifetime prevalence of about 13%. Selective serotonin reuptake inhibitors (SSRIs) ...