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High amount of lecithin facilitates oral delivery of a poorly soluble pyrazoloquinolinone ligand formulated in lipid nanoparticles: Physicochemical, structural and pharmacokinetic performances
(Elsevier B.V., 2023)
Preclinical development of deuterated pyrazoloquinolinone ligands, promising drug candidates for various neuropsychiatric disorders, was hindered by unusually low solubility in water and oils. DK-I-60-3 (7-methoxy-d3- ...
European Analytical Column No. 47
(Springer Heidelberg, Heidelberg, 2019)
Ketamine in a model of depression resistant to tricyclic antidepressants
(Elsevier Science BV, Amsterdam, 2019)
Greener chemistry in analytical sciences: from green solvents to applications in complex matrices. Current challenges and future perspectives: a critical review
(Royal Society of Chemistry, 2023)
More environment-friendly solvents in analytical chemistry are almost inevitable in both sample preparation and analysis to meet the high standards of sustainable chemistry and human welfare. In this review paper, a critical ...
Transgenic mouse, carrier of human CYP2C19 gene, as an animal model for hyperdopaminergism-induced hyperkinesia
(Elsevier Science BV, Amsterdam, 2019)
A novel positive modulator of alpha 4-GABAA receptors, XHe-III-74, reduces ethanol intake in mouse "drinking in the dark" model
(Elsevier Science BV, Amsterdam, 2019)
Integrated in vitro – in vivo – in silico studies in the pharmaceutical development of propranolol hydrochloride mucoadhesive buccal films
(Elsevier, 2023)
In order to exploit the advantage of drug delivery through the buccal mucosa, mucoadhesive buccal films with propranolol hydrochloride based on polyethylene oxide, hydroxypropyl methylcellulose, and polyvinyl alcohol have ...
Novel anti-inflammatory emollient gel: assessment of efficacy in SLS provoked/irritated skin
(Wiley, Hoboken, 2019)
Drugs with a negative impact on cognitive function (Part 1): chronic kidney disease as a risk factor
(Oxford University Press ( Oxford Academic), 2023)
People living with chronic kidney disease (CKD) frequently suffer from mild cognitive impairment and/or other
neurocognitive disorders. This review in two parts will focus on adverse drug reactions resulting in cognitive ...