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Chaotropic chromatography method development for the determination of aripiprazole and its impurities following analytical quality by design principles
(Wiley-VCH Verlag, 2020)
In this paper, development of robust and reliable chaotropic chromatography method for the determination of aripiprazole and its impurities, following Analytical Quality by Design principles is presented. The efficient ...
Relationship between bone resorption, oxidative stress and inflammation in severe COPD exacerbation
(Pergamon-Elsevier Science Ltd, Oxford, 2013)
Background: The natural course of chronic obstructive pulmonary disease (COPD) is complicated by the development of systemic consequences and co-morbidities. Increasing evidence indicates that COPD and osteoporosis are ...
Corona Charged Aerosol Detector in studying retention and β-cyclodextrin complex stability using RP-HPLC
(Elsevier B.V., 2021)
Binding between cyclodextrin (CD) cavity and guest molecule in Reversed Phase High-Performance Liquid Chromatography (RP-HPLC) is dynamic process. In general, increasing CD concentration is inducing inclusion complex ...
Tailored porosity development in carbons via Zn2+ monodispersion: Fitting supercapacitors
(Elsevier B.V., 2022)
Here, we propose a novel, electrochemical preparation of in situ N-doped alginate-based carbon precursors with monodispersed zinc ions. Obtained carbons were evaluated by spectroscopic (FTIR, Raman and XPS), textural (N2 ...
Heavy metal and pesticide exposure: A mixture of potential toxicity and carcinogenicity
(Elsevier B.V., 2020)
There is a growing body of evidence that various pesticides and heavy metals are carcinogenic. If not directly, there is also evidence that shows that these compounds can participate in carcinogenesis in a passive or ...
Pharmacists’ Assessment of the Difficulty and Frequency of Ethical Issues Encountered in Community Pharmacy Settings
(Springer Netherlands, 2019)
Researching ethical problems and their frequency could give us a complex picture and greater insight into the types of ethical issues that pharmacists face in providing health care. The overall aim of this study was to ...
Potential Influence of Tubular Dysfunction on the Difference Between Estimated and Measured Glomerular Filtration Rate After Kidney Transplantation
(Elsevier Science Inc, New York, 2013)
Purpose. Because no consensus exists regarding the most accurate calculation to estimate glomerular filtration rate (GFR) based on serum creatinine concentrations (sCr) after kidney transplantation, this study sought to ...
Functional properties of wheat kernels (Triticumaestivum L.) during storage
(Elsevier, 2020)
The method of storage has, in the long run, a negative effect on the quality of wheat kernels, due to physiological ageing of its cells.The quality of the kernels was assessed during the storage, giving the predefined ...
Design and QSAR study of analogs of gamma-tocotrienol with enhanced anti proliferative activity against human breast cancer cells
(Elsevier Science Inc, New York, 2009)
Quantitative structure-activity relationships (QSAR) study has been performed for two sets of the antitumor drugs against human breast cancer MCF-7 cell lines, alpha-tocopherol and cholesterol derivatives. Constitutional, ...
Monitoring of fosinopril sodium impurities by liquid chromatography-mass spectrometry including the neural networks in method evaluation
(Elsevier Science BV, Amsterdam, 2008)
In this paper, the mass spectrometry (MS) detection has been applied for screening of fosinopril sodium impurities which arise during forced stress study. Before MS analysis, liquid chromatographic method with suitable ...