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Organic nitrates in acute coronary syndrome / Organski nitrati u akutnom koronarnom sindromu
(Klinički centar Srbije, Beograd, 2013)
Large randomized trials have shown that routinely applied nitrates (iv or orally), in acute coronary syndrome (ACS) do not reduce significantly mortality. Nevertheless, nitrates still have a place in therapy of certain ...
Study of chitosan/xanthan gum polyelectrolyte complexes formation, solid state and influence on ibuprofen release kinetics
(Elsevier B.V., 2020)
This study investigated the combined influence of pH adjusting agent type (hydrochloric, acetic or lactic acid) and initial pH value (3.6, 4.6, and 5.6) on formation of biocompatible chitosan/xanthan polyelectrolyte complexes ...
Anti-biofilm Properties of Bacterial Di-Rhamnolipids and Their Semi-Synthetic Amide Derivatives
(Frontiers Media Sa, Lausanne, 2017)
A new strain, namely Lysinibacillus sp. BV152.1 was isolated from the rhizosphere of ground ivy (Glechoma hederacea L.) producing metabolites with potent ability to inhibit biofilm formation of an important human pathogens ...
Ester to amide substitution improves selectivity, efficacy and kinetic behavior of a benzodiazepine positive modulator of GABA(A) receptors containing the alpha 5 subunit
(Elsevier Science BV, Amsterdam, 2016)
We have synthesized and characterized MP-III-022 ((R)-8-ethynyl 6 (2 fluorophenyl)-N,4-dimethyl4H-benzo[f]imidazo[1,5-alpha][1,4]diazepine-3-carboxamide) in vitro and in vivo as a binding- and efficacy selective positive ...
Preanalytical and analytical challenges in gas chromatographic determination of cholesterol synthesis and absorption markers
(Elsevier Science BV, Amsterdam, 2018)
Introduction: Cholesterol homeostasis disruption contributes to the development of different pathologies. Non cholesterol sterols (NCSs) serve as cholesterol synthesis markers (desmosterol and lathosterol), and cholesterol ...
Association of acute Babesia canis infection and serum lipid, lipoprotein, and apoprotein concentrations in dogs
(Blackwell Publishing Inc., 2019)
Background: Babesia canis infection induces a marked acute phase response (APR) that might be associated with alteration in lipid and lipoprotein metabolism and disease prognosis. Hypothesis: Dogs with B. canis-induced APR ...
Interaction of Lactobacillus fermentum BGHI14 with Rat Colonic Mucosa: Implications for Colitis Induction
(Amer Soc Microbiology, Washington, 2013)
The present study was carried out to test the colonic mucosal response of rats to oral supplementation with Lactobacillus fermentum BGHI14 and to correlate the tissue reaction to trinitrobenzenesulfonate (TNBS)-induced ...
Sex differences in the clinical presentation and therapy of multiple sclerosis / Polne razlike u kliničkoj slici i terapiji multiple skleroze
(Savez farmaceutskih udruženja Srbije, Beograd, 2016)
Multiple sclerosis (MS) is more prevalent in women than in men, with the female to male ratio in the prevalence of MS constantly increasing. Besides, sex appears to affect the development, progression, clinical manifestation ...
Development and validation of a stability- indicating RP-HPLC method for determination of aripiprazole and its degradation products / Razvoj i validacija RP-HPLC metode za praćenje stabilnosti u cilju određivanja sadržaja aripiprazola i njegovih degradacionih proizvoda
(Savez farmaceutskih udruženja Srbije (SFUS), 2023)
The goal of this study was the optimization of chromatographic conditions and validation
of the isocratic RP-HPLC method for monitoring the stability of aripiprazole, identification and
quantitative analysis of aripiprazole ...
Neonatal testosterone imprinting affects thymus development and leads to phenotypic rejuvenation and masculinization of the peripheral blood T-cell compartment in adult female rats
(Academic Press Inc Elsevier Science, San Diego, 2009)
Exposure of female rodents to testosterone in the critical neonatal period produces defeminization/masculinization of the hypothalamo-pituitary-gonadal (HPG) axis, i.e. neonatal androgenization and postpones axis maturation. ...