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Non-dioxin-like PCBs in ten different fish species from the Danube river in Serbia
(Springer, Dordrecht, 2011)
This work has been developed to examine the level of non-dioxin-like (ndl) PCBs (28, 52, 101, 138, 153 and 180) in (a) ten different freshwater fish species from the Danube river, (b) two sampling points: up and downstream ...
Impurity profiling of mycophenolate mofetil with the assisstance of desirability function in method development
(Taylor & Francis Inc, Philadelphia, 2011)
Multicriteria decision making methodology in combination with experimental design has been applied for optimization of stability-indicating LC/DAD method of Mycophenolate mofetil and its degradation products. Via fractional ...
Desirability-based optimization and its sensitivity analysis for the perindopril and its impurities analysis in a microemulsion LC system
(Elsevier Science BV, Amsterdam, 2011)
In the current paper the application of multiobjective optimization (MOOP) technique, via Derringer's desirability function, to a microemulsion liquid chromatographic (MELC) method is described. Chromatographic separation ...
Drug stability: Industry view / Stabilnost lekova - industrijski aspect
(Savez farmaceutskih udruženja Srbije, Beograd, 2011)
Stability testing is carried out in several phases of new product development. The effect of various external factors on possible formulations, compatibility of active pharmaceutical ingredient, excipients and primary ...
Predicting absorption and pharmacokinetic profile of carbamazepine from controlled-release tablet formulation in humans using rabbit model / Predviđanje resorpcije i farmakokinetičkog profila karbamazepina iz tableta sa kontrolisanim oslobađanjem kod ljudi korišćenjem modela kunića
(Univerzitet u Beogradu - Fakultet veterinarske medicine, Beograd, 2011)
Controlled-release (CR) pharmaceutical formulations offer several advantages over the conventional, immediate release dosage forms of the same drug, including reduced dosing frequency, decreased incidence and/or intensity ...
HPLC evaluation of solvolysis of a novel ester fluocinolone acetonide 21-(2'-phenoxypropionate) in comparison with fluocinonide
(Taylor & Francis Inc, Philadelphia, 2011)
In this study the solvolysis of novel fluocinolone acetonide 21-(2'-phenoxypropionate) in comparison with fluocinonide was analyzed in order to evaluate this process as an in vitro model for prodrug activation. The solvolysis ...
A Useful Synthetic Equivalent of a Hydroxyacetone Enolate
(Amer Chemical Soc, Washington, 2011)
Indium promoted allyiation of carbonyl compounds with 4-(bromomethyl)-1,3-dioxol-2-one diastereoselectively affords and-alpha,beta-dihydroxyketones, protected as enol carbonates. These initial products can be deprotected ...
Evaluation of Renal Damage by Urinary Beta-Trace Protein in Patients with Chronic Kidney Disease
(Clin Lab Publ, Heidelberg, 2011)
Background: Beta-trace protein (BTP) was found to be increased in the serum and urine of patients with renal diseases. The aim of this study was to compare the urinary levels of beta-trace protein with levels of other ...
An investigation of formulation factors affecting feasibility of alginate-chitosan microparticles for oral delivery of naproxen
(Pharmaceutical Soc Korea, Seoul, 2011)
In the present work we investigated the feasibility of chitosan treated Ca-alginate microparticles for delivery of naproxen in lower parts of GIT and evaluated influence of formulation factors on their physicochemical ...
Stability, bifurcations, and dynamics of global variables of a system of bursting neurons
(Amer Inst Physics, Melville, 2011)
An approximate mean field model of an ensemble of delayed coupled stochastic Hindmarsh-Rose bursting neurons is constructed and analyzed. Bifurcation analysis of the approximate system is performed using numerical continuation. ...