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Ester to amide substitution improves selectivity, efficacy and kinetic behavior of a benzodiazepine positive modulator of GABA(A) receptors containing the alpha 5 subunit
(Elsevier Science BV, Amsterdam, 2016)
We have synthesized and characterized MP-III-022 ((R)-8-ethynyl 6 (2 fluorophenyl)-N,4-dimethyl4H-benzo[f]imidazo[1,5-alpha][1,4]diazepine-3-carboxamide) in vitro and in vivo as a binding- and efficacy selective positive ...
Non-dioxin-like PCBs in ten different fish species from the Danube river in Serbia
(Springer, Dordrecht, 2011)
This work has been developed to examine the level of non-dioxin-like (ndl) PCBs (28, 52, 101, 138, 153 and 180) in (a) ten different freshwater fish species from the Danube river, (b) two sampling points: up and downstream ...
Determination of S-carboxymethyl-L-cysteine, methylparaben and their degradation products in syrup preparations
(Springer Heidelberg, Heidelberg, 2004)
An HPLC method was developed for the determination of S-carboxymethyl-L-cysteine, methylparaben and related compounds in cough syrup preparations. The HPLC operating conditions used were acetonitrile-methanol-water ...
Catecholaminergic signalling through thymic nerve fibres, thymocytes and stromal cells is dependent on both circulating and locally synthesized glucocorticoids
(Wiley-Blackwell, Hoboken, 2012)
Glucocorticoids have been shown to modulate the expression of noradrenaline metabolizing enzymes and beta(2)- and alpha(1B)-adrenoceptors in a tissue- and cell- specific manner. In the thymus, apart from extensive sympathetic ...
Cardiovascular risk estimated by UKPDS risk engine algorithm in diabetes
(Sciendo, Warsaw, 2018)
Since there is a high prevalence of type 2 diabetes mellitus (DM2), as well as CVD in Montenegro, we aimed to estimate CVD risk by United Kingdom Prospective Diabetes Study (UKPDS) risk engine algorithm in individuals with ...
Retinol-binding protein 4 versus albuminuria as predictors of estimated glomerular filtration rate decline in patients with type 2 diabetes
(Wolters Kluwer Medknow Publications, Mumbai, 2018)
Background:Since the increase in some tubular damage biomarkers can be observed at the early stage of diabetic nephropathy, even in the absence of albuminuria, we aimed to investigate if urinary albumin is superior than ...
The Applications of New Inorganic Polymer for Adsorption Cadmium from Waste Water
(Springer Nature, 2020)
Fundamental research of inorganic polymers prepared from available aluminosilicate precursors represent an innovative class of materials characterized by low energy consumption for production. This is just one of the reasons ...
Experimental design in chromatographic analysis of pramipexole and its impurities
(Slovensko Kemijsko Drustvo, Ljubljana, 2007)
Pramipexole is a dopamine D2-agonist/antiparkinsonian agent in which BI-II 546 CL, BI-II 751 xx and 2-amino benzothiazole are commonly found as impurities. Due to the lack of analytical data on pramipexole and its related ...
Total antioxidant status in coronary artery disease patients
(Elsevier Ireland Ltd, Clare, 2010)
Sources of supplementary vitamins and minerals in Serbian nutrition
(Karger, Basel, 2009)