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Quality by Design approach in the development of hydrophilic interaction liquid chromatographic method for the analysis of iohexol and its impurities
(Elsevier Science BV, Amsterdam, 2015)
This study presents the development of hydrophilic interaction liquid chromatographic method for the analysis of iohexol, its endo-isomer and three impurities following Quality by Design (QbD) approach. The main objective ...
Quality by Design Determination of Diclofenac Potassium and its Impurities by High-Performance Liquid Chromatography
(Taylor & Francis Inc, Philadelphia, 2016)
A liquid chromatography method is reported for the determination of diclofenac potassium and its impurities using Quality by Design criteria. Central composite design was used for the investigation of the influence of ...
Application of the fractional factorial design in multiple W/O/W emulsions
(Taylor & Francis Inc, Philadelphia, 2017)
In presented research, multiple W/O/W emulsions were developed by using experimental design method. A 24-1 fractional factorial design was performed by varying the following input parameters: primary polymeric emulsifier ...
Functionality of chitosan‐halloysite nanocomposite films for sustained delivery of antibiotics: The effect of chitosan molar mass
(Wiley Periodicals, Inc., 2020)
This study was designed to investigate functionality of tetracycline‐loaded chitosan‐halloysite nanocomposite films, with focus on evaluating the influence of chitosan molar mass on films applicability for sustained local ...
Formulation and characterization of nanofibers and films with carvedilol prepared by electrospinning and solution casting method
(Elsevier Science BV, Amsterdam, 2017)
The preparation and characterization of films and nanofibers with carvedilol as a poorly water-soluble drug in poly (ethylene oxide) (PEO) polymer were investigated. Films are prepared by solution casting method, and ...
Estimation of passive gastrointestinal absorption and membrane retention using PAMPA test, quantitative structure-permeability and quantitative structure-retention relationship analyses of ethylenediamine-N,N'-di-2-(3-cyclohexyl)propanoic acid and 1,3-propanediamine-N,N'-di-2-(3-cyclohexyl)propanoic acid derivatives
(Elsevier B.V., 2020)
Passive gastrointestinal absorption and membrane retention of twelve esters of (S,S)-ethylenediamine-N,N'-di-2-(3-cyclohexyl)propanoic acid (EDCP) and (S,S)-1,3-propanediamine-N,N'-di-2-(3-cyclohexyl)propanoic acid (PDCP), ...
Antioxidant and antimicrobial activity of Cynara cardunculus extracts
(Elsevier Sci Ltd, Oxford, 2008)
The whole, fresh involucral bracts of cardoon, Cynara cardunculus L. (Compositae), were extracted with EtOH and an aqueous suspension of the obtained EtOH extract was partitioned successively with CHCl3, EtOAc and n-BuOH, ...
Implications of oxidative stress in occupational exposure to lead on a cellular level
(Taylor & Francis Ltd, Abingdon, 2015)
The aim of this study was to determine oxidative alterations leading to cellular dysfunctions in Pb-exposed subjects by evaluating damage to all major classes of biomolecules in the cell, lipid peroxidation, protein and ...
Quantitative Structure-Activity Relationships of xanthen-3-one and xanthen-1,8-dione derivatives and design of new compounds with enhanced antiproliferative activity on HeLa cervical cancer cells
(Taylor & Francis, 2021)
Xanthene derivatives have become a group of molecules of great importance in discovering of
new anticancer drugs. Recent studies of our group performed on xanthen-3-one and xanthen-
1,8-dione derivatives have shown their ...
Antigenotoxic and antioxidant potential of medicinal mushrooms (Immune Assist) against DNA damage induced by free radicals-an in vitro study
(Elsevier, 2019)
Immune Assist (IA) is produced from extract of six species of medical mushrooms: Agaricus blazei - Cordyceps sinensis - Grifola frondosa - Ganoderma lucidum - Coriolus versicolor - Lentinula edodes. The genoprotective ...