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Computer-aided formulation development
(Elsevier Inc., 2013)
This chapter introduces the concept of formulation development assisted by computer applications. Development and optimization of various types of pharmaceutical emulsions microemulsions, self-microemulsifying systems, and ...
Zinc, copper or magnesium supplementation against cadmium toxicity: An experimental study
(Nova Science Publishers, Inc., 2011)
Cadmium (Cd) is currently one of the most important toxic metals in occupational and environmental toxicology. It causes adverse effects on kidneys, liver, lungs, bones, testes, etc, and is classified in group 1 of human ...
Alkyl Polyglucoside-based delivery systems: In vitro/in vivo skin absorption assessment
(Elsevier Inc., 2014)
Skin permeation and penetration assessment is important not only for determining efficacy of a topical product, but also when comparing different formulations during development. This chapter reviews methods for dermal ...
Percutaneous penetration enhancement potential of microemulsion-based organogels
(Springer Berlin Heidelberg, 2016)
The skin, and particularly the most outer layer stratum corneum, is an effective barrier for molecules administered by conventional topical formulations (i.e., ointments, creams, hydrogels). Therefore, vehicles and carriers ...
Properties and biomedical relevance of phytosome encapsulated polyphenolics
(Nova Science Publisher Inc., 2017)
Polyphenols are secondary metabolites of plants, containing in their structure the aromatic ring with one or more phenolic groups. Such molecules have great antioxidant potential. They can modulate the activity of many ...
QSRR Approach: Application to Retention Mechanism in Liquid Chromatography
(IntechOpen, 2023)
One-factor-at-a-time experimentation was used for a long time as gold-standard
optimization for liquid chromatographic (LC) method development. This approach
has two downsides as it requires a needlessly great number of ...
Natural Surfactants-Based Micro/Nanoemulsion Systems for NSAIDs- Practical Formulation Approach, Physicochemical and Biopharmaceutical Characteristics/Performances
(Elsevier Inc., 2017)
Considering the superior advantages over traditional formulation approaches, micro/nanoemulsions represent very attractive carriers worth exploring for improving dermal/transdermal delivery of NSAIDs. Currently, natural-origin ...
Natural emulsifiers of the alkyl polyglucoside type and their influence on the permeation of drugs
(Springer Berlin Heidelberg, 2015)
Due to the unceasing progress in design of novel emulsifiers, powerful influence of the ongoing ‘green’ trends in cosmetic industry, but also global environmental concerns, there is an increasing demand in development and ...
Emulsion systems: From stability concerns to sensory properties
(Elsevier Inc., 2014)
Emulsions need to fulfil many demands and expectations regarding stability, safety and efficacy on the one hand, and sensory properties on the other, in order to be acceptable to consumers. For stability and sensory ...
Behind the Alkyl Polyglucoside-based structures: Lamellar liquid crystalline and lamellar gel phases in different emulsion systems
(Elsevier Inc., 2014)
Surfactants play an important role in the development of colloidal delivery systems for cosmetics and pharmaceutical ingredients. Alkyl Polyglucosides (APGs) show peculiar physicochemical behaviour, which affects their ...