Smaller HDL particles are associated with absence of obstructive coronary artery disease in stable angina pectoris patients
2014
Аутори
Zeljković, AleksandraVekić, Jelena
Spasojević-Kalimanovska, Vesna
Jelić-Ivanović, Zorana
Kalimanovska-Oštrić, Dimitra
Memon, Lidija
Bogavac-Stanojević, Nataša
Topić, Aleksandra
Spasić, Slavica
Чланак у часопису (Објављена верзија)
Метаподаци
Приказ свих података о документуАпстракт
Background A research on novel cardiovascular risk factors is mainly focused on patients with clinically verified coronary artery disease (CAD), while less is known about their presence in symptomatic patients, but without angiographically proven occlusion of coronary arteries. The aim of this study was to compare plasma low-density lipoprotein (LDL) and high-density lipoprotein (HDL) size and subclasses in stable angina patients with and without significant obstructive CAD. Methods LDL and HDL subclasses were analysed in 100 stable angina patients with >= 50% of obstruction and 40 patients with less than 50% of luminal narrowing, as assessed by coronary angiography. Results Patients with lt 50% of obstruction had reduced mean HDL size and higher proportion of small HDL particles (P lt 0.05). HDL size and proportion of small HDL particles were significant and independent predictors of obstructive CAD (P lt 0.05, respectively). Conclusions Stable angina patients with
Кључне речи:
dyslipidemia / LDL and HDL subclasses / central adiposity / non-obstructive coronary artery diseaseИзвор:
Annals of Clinical Biochemistry, 2014, 51, 3, 412-415Издавач:
- Sage Publications Inc, Thousand Oaks
Финансирање / пројекти:
- Интерактивна улога дислипидемије, оксидативног стреса и инфламације у атеросклерози и другим болестима: генетички и биохемијски маркери (RS-MESTD-Basic Research (BR or ON)-175035)
DOI: 10.1177/0004563213499908
ISSN: 0004-5632
PubMed: 24031042
WoS: 000334175600014
Scopus: 2-s2.0-84898677950
Институција/група
PharmacyTY - JOUR AU - Zeljković, Aleksandra AU - Vekić, Jelena AU - Spasojević-Kalimanovska, Vesna AU - Jelić-Ivanović, Zorana AU - Kalimanovska-Oštrić, Dimitra AU - Memon, Lidija AU - Bogavac-Stanojević, Nataša AU - Topić, Aleksandra AU - Spasić, Slavica PY - 2014 UR - https://farfar.pharmacy.bg.ac.rs/handle/123456789/2164 AB - Background A research on novel cardiovascular risk factors is mainly focused on patients with clinically verified coronary artery disease (CAD), while less is known about their presence in symptomatic patients, but without angiographically proven occlusion of coronary arteries. The aim of this study was to compare plasma low-density lipoprotein (LDL) and high-density lipoprotein (HDL) size and subclasses in stable angina patients with and without significant obstructive CAD. Methods LDL and HDL subclasses were analysed in 100 stable angina patients with >= 50% of obstruction and 40 patients with less than 50% of luminal narrowing, as assessed by coronary angiography. Results Patients with lt 50% of obstruction had reduced mean HDL size and higher proportion of small HDL particles (P lt 0.05). HDL size and proportion of small HDL particles were significant and independent predictors of obstructive CAD (P lt 0.05, respectively). Conclusions Stable angina patients with PB - Sage Publications Inc, Thousand Oaks T2 - Annals of Clinical Biochemistry T1 - Smaller HDL particles are associated with absence of obstructive coronary artery disease in stable angina pectoris patients VL - 51 IS - 3 SP - 412 EP - 415 DO - 10.1177/0004563213499908 ER -
@article{ author = "Zeljković, Aleksandra and Vekić, Jelena and Spasojević-Kalimanovska, Vesna and Jelić-Ivanović, Zorana and Kalimanovska-Oštrić, Dimitra and Memon, Lidija and Bogavac-Stanojević, Nataša and Topić, Aleksandra and Spasić, Slavica", year = "2014", abstract = "Background A research on novel cardiovascular risk factors is mainly focused on patients with clinically verified coronary artery disease (CAD), while less is known about their presence in symptomatic patients, but without angiographically proven occlusion of coronary arteries. The aim of this study was to compare plasma low-density lipoprotein (LDL) and high-density lipoprotein (HDL) size and subclasses in stable angina patients with and without significant obstructive CAD. Methods LDL and HDL subclasses were analysed in 100 stable angina patients with >= 50% of obstruction and 40 patients with less than 50% of luminal narrowing, as assessed by coronary angiography. Results Patients with lt 50% of obstruction had reduced mean HDL size and higher proportion of small HDL particles (P lt 0.05). HDL size and proportion of small HDL particles were significant and independent predictors of obstructive CAD (P lt 0.05, respectively). Conclusions Stable angina patients with", publisher = "Sage Publications Inc, Thousand Oaks", journal = "Annals of Clinical Biochemistry", title = "Smaller HDL particles are associated with absence of obstructive coronary artery disease in stable angina pectoris patients", volume = "51", number = "3", pages = "412-415", doi = "10.1177/0004563213499908" }
Zeljković, A., Vekić, J., Spasojević-Kalimanovska, V., Jelić-Ivanović, Z., Kalimanovska-Oštrić, D., Memon, L., Bogavac-Stanojević, N., Topić, A.,& Spasić, S.. (2014). Smaller HDL particles are associated with absence of obstructive coronary artery disease in stable angina pectoris patients. in Annals of Clinical Biochemistry Sage Publications Inc, Thousand Oaks., 51(3), 412-415. https://doi.org/10.1177/0004563213499908
Zeljković A, Vekić J, Spasojević-Kalimanovska V, Jelić-Ivanović Z, Kalimanovska-Oštrić D, Memon L, Bogavac-Stanojević N, Topić A, Spasić S. Smaller HDL particles are associated with absence of obstructive coronary artery disease in stable angina pectoris patients. in Annals of Clinical Biochemistry. 2014;51(3):412-415. doi:10.1177/0004563213499908 .
Zeljković, Aleksandra, Vekić, Jelena, Spasojević-Kalimanovska, Vesna, Jelić-Ivanović, Zorana, Kalimanovska-Oštrić, Dimitra, Memon, Lidija, Bogavac-Stanojević, Nataša, Topić, Aleksandra, Spasić, Slavica, "Smaller HDL particles are associated with absence of obstructive coronary artery disease in stable angina pectoris patients" in Annals of Clinical Biochemistry, 51, no. 3 (2014):412-415, https://doi.org/10.1177/0004563213499908 . .