Alkyl Polyglucoside-based delivery systems: In vitro/in vivo skin absorption assessment
Само за регистроване кориснике
2014
Поглавље у монографији (Објављена верзија)
Метаподаци
Приказ свих података о документуАпстракт
Skin permeation and penetration assessment is important not only for determining efficacy of a topical product, but also when comparing different formulations during development. This chapter reviews methods for dermal availability assessment of delivery systems, with their advantages and shortcomings, and examples of their practical application with Alkyl Polyglucoside-based preparations. Alkyl Polyglucosides are used in many different delivery systems with various model actives. Systems stabilized with Alkyl Polyglucoside surfactants provide highly satisfactory cutaneous delivery compared with reference samples. This is mainly attributed to the characteristic APG-based colloidal structure and its ability to provide a combined enhancing effect with co-solvents. Microemulsions for dermal/transdermal delivery are also becoming popular due to their high solubilization potential. Alkyl Polyglucoside surfactants are also being considered for development of nanosystems.
Кључне речи:
Dermal availability / Diffusion cells / Enhancer cells / Skin blanching assay / Skin penetration assessment / Skin permeation assessment / Tape stripping techniqueИзвор:
Alkyl Polyglucosides: From Natural-Origin Surfactants to Prospective Delivery Systems, 2014, 107-134Издавач:
- Elsevier Inc.
Институција/група
PharmacyTY - CHAP AU - Pantelić, Ivana AU - Lukić, Milica AU - Daniels, Rolf AU - Savić, Snežana PY - 2014 UR - https://farfar.pharmacy.bg.ac.rs/handle/123456789/2246 AB - Skin permeation and penetration assessment is important not only for determining efficacy of a topical product, but also when comparing different formulations during development. This chapter reviews methods for dermal availability assessment of delivery systems, with their advantages and shortcomings, and examples of their practical application with Alkyl Polyglucoside-based preparations. Alkyl Polyglucosides are used in many different delivery systems with various model actives. Systems stabilized with Alkyl Polyglucoside surfactants provide highly satisfactory cutaneous delivery compared with reference samples. This is mainly attributed to the characteristic APG-based colloidal structure and its ability to provide a combined enhancing effect with co-solvents. Microemulsions for dermal/transdermal delivery are also becoming popular due to their high solubilization potential. Alkyl Polyglucoside surfactants are also being considered for development of nanosystems. PB - Elsevier Inc. T2 - Alkyl Polyglucosides: From Natural-Origin Surfactants to Prospective Delivery Systems T1 - Alkyl Polyglucoside-based delivery systems: In vitro/in vivo skin absorption assessment SP - 107 EP - 134 DO - 10.1533/9781908818775.107 ER -
@inbook{ author = "Pantelić, Ivana and Lukić, Milica and Daniels, Rolf and Savić, Snežana", year = "2014", abstract = "Skin permeation and penetration assessment is important not only for determining efficacy of a topical product, but also when comparing different formulations during development. This chapter reviews methods for dermal availability assessment of delivery systems, with their advantages and shortcomings, and examples of their practical application with Alkyl Polyglucoside-based preparations. Alkyl Polyglucosides are used in many different delivery systems with various model actives. Systems stabilized with Alkyl Polyglucoside surfactants provide highly satisfactory cutaneous delivery compared with reference samples. This is mainly attributed to the characteristic APG-based colloidal structure and its ability to provide a combined enhancing effect with co-solvents. Microemulsions for dermal/transdermal delivery are also becoming popular due to their high solubilization potential. Alkyl Polyglucoside surfactants are also being considered for development of nanosystems.", publisher = "Elsevier Inc.", journal = "Alkyl Polyglucosides: From Natural-Origin Surfactants to Prospective Delivery Systems", booktitle = "Alkyl Polyglucoside-based delivery systems: In vitro/in vivo skin absorption assessment", pages = "107-134", doi = "10.1533/9781908818775.107" }
Pantelić, I., Lukić, M., Daniels, R.,& Savić, S.. (2014). Alkyl Polyglucoside-based delivery systems: In vitro/in vivo skin absorption assessment. in Alkyl Polyglucosides: From Natural-Origin Surfactants to Prospective Delivery Systems Elsevier Inc.., 107-134. https://doi.org/10.1533/9781908818775.107
Pantelić I, Lukić M, Daniels R, Savić S. Alkyl Polyglucoside-based delivery systems: In vitro/in vivo skin absorption assessment. in Alkyl Polyglucosides: From Natural-Origin Surfactants to Prospective Delivery Systems. 2014;:107-134. doi:10.1533/9781908818775.107 .
Pantelić, Ivana, Lukić, Milica, Daniels, Rolf, Savić, Snežana, "Alkyl Polyglucoside-based delivery systems: In vitro/in vivo skin absorption assessment" in Alkyl Polyglucosides: From Natural-Origin Surfactants to Prospective Delivery Systems (2014):107-134, https://doi.org/10.1533/9781908818775.107 . .