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Influence of Polycation Functional Properties on Polyanion Micro/Nanoparticles for NSAIDs Reinforced via Polyelectrolyte Complexation: Alginate-Chitosan Case Study
dc.creator | Čalija, Bojan | |
dc.creator | Cekić, Nebojša | |
dc.creator | Milić, Jela | |
dc.date.accessioned | 2019-09-02T11:57:13Z | |
dc.date.available | 2019-09-02T11:57:13Z | |
dc.date.issued | 2017 | |
dc.identifier.uri | https://farfar.pharmacy.bg.ac.rs/handle/123456789/2789 | |
dc.description.abstract | In the last 2 decades, numerous studies have been carried out to synthesize biodegradable and nontoxic micro- and nanoparticulate carriers for nonsteroidal anti-inflammatory drugs. The potential benefits of these carriers are reduction of dosing frequency and minimization of side effects due to prolonged/delayed drug release, increased selectivity for target tissues and possibility of direct administration to the site of action.This chapter discusses characteristics of alginate-based micro- and nanoparticles reinforced with chitosan and gives an overview of the techniques commonly used for preparation of these drug carriers. It is focused on the chitosans' functionality-related characteristics, such as molecular weight and viscosity, and their influence on feasibility of the alginate-chitosan particulate carriers for oral delivery of nonsteroidal anti-inflammatory drugs. Additionally, chitosan's structure, safety, and overall characteristics are discussed in detail for better understanding. | en |
dc.publisher | Elsevier Inc. | |
dc.relation | info:eu-repo/grantAgreement/MESTD/Technological Development (TD or TR)/34031/RS// | |
dc.rights | restrictedAccess | |
dc.source | Microsized and Nanosized Carriers for Nonsteroidal Anti-Inflammatory Drugs: Formulation Challenges a | |
dc.subject | Alginate | en |
dc.subject | Chitosan | en |
dc.subject | Chitosan's functionality | en |
dc.subject | Microparticles | en |
dc.subject | Nanoparticles | en |
dc.subject | Nonsteroidal anti-inflammatory drugs | en |
dc.title | Influence of Polycation Functional Properties on Polyanion Micro/Nanoparticles for NSAIDs Reinforced via Polyelectrolyte Complexation: Alginate-Chitosan Case Study | en |
dc.type | bookPart | |
dc.rights.license | ARR | |
dcterms.abstract | Милић, Јела; Цекић, Небојша; Чалија, Бојан; | |
dc.citation.spage | 133 | |
dc.citation.epage | 160 | |
dc.citation.other | : 133-160 | |
dc.identifier.doi | 10.1016/B978-0-12-804017-1.00005-4 | |
dc.identifier.scopus | 2-s2.0-85022174310 | |
dc.type.version | publishedVersion |