Derivative spectrophotometric method for determination of acidity constants of single step acid-base equilibria
Abstract
A general derivative spectrophotometric method for determination of acidity constants is developed. The method appears suitable in cases when classical spectrophotometry cannot be employed due to little differences in the absorption spectra of conjugated acid-base pairs. Based on theoretical considerations, seven variants of the method have been established and their validity was checked, determining acidity constants of lorazepam and flurazepam as model compounds.
Source:
Talanta, 2001, 55, 2, 363-370Publisher:
- Elsevier Science BV, Amsterdam
DOI: 10.1016/S0039-9140(01)00433-7
ISSN: 0039-9140
PubMed: 18968381
WoS: 000171174600018
Scopus: 2-s2.0-0035974972
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Institution/Community
PharmacyTY - JOUR AU - Popović, Gordana AU - Pfendt, Lidija AU - Moskovljević, VM PY - 2001 UR - https://farfar.pharmacy.bg.ac.rs/handle/123456789/300 AB - A general derivative spectrophotometric method for determination of acidity constants is developed. The method appears suitable in cases when classical spectrophotometry cannot be employed due to little differences in the absorption spectra of conjugated acid-base pairs. Based on theoretical considerations, seven variants of the method have been established and their validity was checked, determining acidity constants of lorazepam and flurazepam as model compounds. PB - Elsevier Science BV, Amsterdam T2 - Talanta T1 - Derivative spectrophotometric method for determination of acidity constants of single step acid-base equilibria VL - 55 IS - 2 SP - 363 EP - 370 DO - 10.1016/S0039-9140(01)00433-7 ER -
@article{ author = "Popović, Gordana and Pfendt, Lidija and Moskovljević, VM", year = "2001", abstract = "A general derivative spectrophotometric method for determination of acidity constants is developed. The method appears suitable in cases when classical spectrophotometry cannot be employed due to little differences in the absorption spectra of conjugated acid-base pairs. Based on theoretical considerations, seven variants of the method have been established and their validity was checked, determining acidity constants of lorazepam and flurazepam as model compounds.", publisher = "Elsevier Science BV, Amsterdam", journal = "Talanta", title = "Derivative spectrophotometric method for determination of acidity constants of single step acid-base equilibria", volume = "55", number = "2", pages = "363-370", doi = "10.1016/S0039-9140(01)00433-7" }
Popović, G., Pfendt, L.,& Moskovljević, V.. (2001). Derivative spectrophotometric method for determination of acidity constants of single step acid-base equilibria. in Talanta Elsevier Science BV, Amsterdam., 55(2), 363-370. https://doi.org/10.1016/S0039-9140(01)00433-7
Popović G, Pfendt L, Moskovljević V. Derivative spectrophotometric method for determination of acidity constants of single step acid-base equilibria. in Talanta. 2001;55(2):363-370. doi:10.1016/S0039-9140(01)00433-7 .
Popović, Gordana, Pfendt, Lidija, Moskovljević, VM, "Derivative spectrophotometric method for determination of acidity constants of single step acid-base equilibria" in Talanta, 55, no. 2 (2001):363-370, https://doi.org/10.1016/S0039-9140(01)00433-7 . .