Lignocellulosic biomass as a source of microcrystalline cellulose - chemical and technological characterization and future perspectives
Само за регистроване кориснике
2018
Аутори
Krstić, MarkoMaksimović, Zoran
Ibrić, Svetlana
Bakić, Tamara
Prodanović, Jovana
Ražić, Slavica
Чланак у часопису (Објављена верзија)
Метаподаци
Приказ свих података о документуАпстракт
In this paper, agricultural waste (corn stover and wheat straw) was used for isolation of microcrystalline cellulose (MCC). Lignocellulosic biomass is widely available and applying smart technologies to valorise it will have a double benefit through environmental protection and achieving high-performance materials for targeted applications. The obtained MCC showed excellent features in terms of purity, physical-chemical properties and safety, as well. The methods applied for characterizing the materials were as follows: FT-IR, SEM, ICP-AAE and IC. Then, tablets were made by the compression method, using the isolated and purified MCC, as well as its commercially available counterpart. Excellent technological characteristics were confirmed by testing material compaction, compactibility, compressibility and drug release. This was one of the first tests in which Gamlen Tableting D was applied, especially in the case of using biomass, in the first phase, with prospects of application at a l...arge scale, particularly, in the pharmaceutical industry.
Кључне речи:
microcrystalline cellulose / corn stover / wheat straw / compactibility / compressibility / employment of agricultural residuesИзвор:
Cellulose Chemistry and Technology, 2018, 52, 7-8, 577-588Издавач:
- Editura Acad Romane, Bucuresti
Финансирање / пројекти:
- Развој производа и технологија које обезбеђују жељено ослобађање лековитих супстанци из чврстих фармацеутских облика (RS-34007)
- Испитивање лековитог потенцијала биљака: морфолошка, хемијска и фармаколошка карактеризација (RS-173021)
- Идентификација специфичних гена за терапију канцера (RS-143009)
Институција/група
PharmacyTY - JOUR AU - Krstić, Marko AU - Maksimović, Zoran AU - Ibrić, Svetlana AU - Bakić, Tamara AU - Prodanović, Jovana AU - Ražić, Slavica PY - 2018 UR - https://farfar.pharmacy.bg.ac.rs/handle/123456789/3137 AB - In this paper, agricultural waste (corn stover and wheat straw) was used for isolation of microcrystalline cellulose (MCC). Lignocellulosic biomass is widely available and applying smart technologies to valorise it will have a double benefit through environmental protection and achieving high-performance materials for targeted applications. The obtained MCC showed excellent features in terms of purity, physical-chemical properties and safety, as well. The methods applied for characterizing the materials were as follows: FT-IR, SEM, ICP-AAE and IC. Then, tablets were made by the compression method, using the isolated and purified MCC, as well as its commercially available counterpart. Excellent technological characteristics were confirmed by testing material compaction, compactibility, compressibility and drug release. This was one of the first tests in which Gamlen Tableting D was applied, especially in the case of using biomass, in the first phase, with prospects of application at a large scale, particularly, in the pharmaceutical industry. PB - Editura Acad Romane, Bucuresti T2 - Cellulose Chemistry and Technology T1 - Lignocellulosic biomass as a source of microcrystalline cellulose - chemical and technological characterization and future perspectives VL - 52 IS - 7-8 SP - 577 EP - 588 UR - https://hdl.handle.net/21.15107/rcub_farfar_3137 ER -
@article{ author = "Krstić, Marko and Maksimović, Zoran and Ibrić, Svetlana and Bakić, Tamara and Prodanović, Jovana and Ražić, Slavica", year = "2018", abstract = "In this paper, agricultural waste (corn stover and wheat straw) was used for isolation of microcrystalline cellulose (MCC). Lignocellulosic biomass is widely available and applying smart technologies to valorise it will have a double benefit through environmental protection and achieving high-performance materials for targeted applications. The obtained MCC showed excellent features in terms of purity, physical-chemical properties and safety, as well. The methods applied for characterizing the materials were as follows: FT-IR, SEM, ICP-AAE and IC. Then, tablets were made by the compression method, using the isolated and purified MCC, as well as its commercially available counterpart. Excellent technological characteristics were confirmed by testing material compaction, compactibility, compressibility and drug release. This was one of the first tests in which Gamlen Tableting D was applied, especially in the case of using biomass, in the first phase, with prospects of application at a large scale, particularly, in the pharmaceutical industry.", publisher = "Editura Acad Romane, Bucuresti", journal = "Cellulose Chemistry and Technology", title = "Lignocellulosic biomass as a source of microcrystalline cellulose - chemical and technological characterization and future perspectives", volume = "52", number = "7-8", pages = "577-588", url = "https://hdl.handle.net/21.15107/rcub_farfar_3137" }
Krstić, M., Maksimović, Z., Ibrić, S., Bakić, T., Prodanović, J.,& Ražić, S.. (2018). Lignocellulosic biomass as a source of microcrystalline cellulose - chemical and technological characterization and future perspectives. in Cellulose Chemistry and Technology Editura Acad Romane, Bucuresti., 52(7-8), 577-588. https://hdl.handle.net/21.15107/rcub_farfar_3137
Krstić M, Maksimović Z, Ibrić S, Bakić T, Prodanović J, Ražić S. Lignocellulosic biomass as a source of microcrystalline cellulose - chemical and technological characterization and future perspectives. in Cellulose Chemistry and Technology. 2018;52(7-8):577-588. https://hdl.handle.net/21.15107/rcub_farfar_3137 .
Krstić, Marko, Maksimović, Zoran, Ibrić, Svetlana, Bakić, Tamara, Prodanović, Jovana, Ražić, Slavica, "Lignocellulosic biomass as a source of microcrystalline cellulose - chemical and technological characterization and future perspectives" in Cellulose Chemistry and Technology, 52, no. 7-8 (2018):577-588, https://hdl.handle.net/21.15107/rcub_farfar_3137 .