Endocrine-disrupting mechanisms of polychlorinated biphenyls
Samo za registrovane korisnike
2020
Autori
Buha-Đorđević, AleksandraAntonijević, Evica
Ćurčić, Marijana
Milovanović, Vesna
Antonijević, Biljana
Članak u časopisu (Objavljena verzija)
Metapodaci
Prikaz svih podataka o dokumentuApstrakt
The extent of human exposure to chemicals, their endocrine-disrupting mechanisms of action, and the relationship between exposure and various human diseases raise significant scientific and public health concerns. Polychlorinated biphenyls (PCBs) belong to the group of organic compounds known as persistent organic pollutants, characterized by long-range transport, persistence, bioaccumulation, and high toxicity. They have been identified as endocrine-disrupting chemicals. In vivo and in vitro studies have shown that endocrine-disrupting effects of PCBs mainly involve thyroid and reproductive function. In the review presented, these effects were placed in the context of the most recent findings on PCB-induced endocrine-disrupting mechanisms and modes of action.
Ključne reči:
Mechanisms and modes of actions / Polychlorinated biphenyls / Reproductive endocrine disruption / Thyroid disruptionIzvor:
Current Opinion in Toxicology, 2020, 19, 42-49Izdavač:
- Elsevier
Finansiranje / projekti:
- Unapređenje i razvoj higijenskih i tehnoloških postupaka u proizvodnji namirnica životinjskog porekla u cilju dobijanja kvalitetnih i bezbednih proizvoda konkurentnih na svetskom tržištu (RS-MESTD-Integrated and Interdisciplinary Research (IIR or III)-46009)
DOI: 10.1016/j.cotox.2019.10.006
ISSN: 2468-2020
WoS: 000531649300009
Scopus: 2-s2.0-85075071571
Institucija/grupa
PharmacyTY - JOUR AU - Buha-Đorđević, Aleksandra AU - Antonijević, Evica AU - Ćurčić, Marijana AU - Milovanović, Vesna AU - Antonijević, Biljana PY - 2020 UR - https://farfar.pharmacy.bg.ac.rs/handle/123456789/3470 AB - The extent of human exposure to chemicals, their endocrine-disrupting mechanisms of action, and the relationship between exposure and various human diseases raise significant scientific and public health concerns. Polychlorinated biphenyls (PCBs) belong to the group of organic compounds known as persistent organic pollutants, characterized by long-range transport, persistence, bioaccumulation, and high toxicity. They have been identified as endocrine-disrupting chemicals. In vivo and in vitro studies have shown that endocrine-disrupting effects of PCBs mainly involve thyroid and reproductive function. In the review presented, these effects were placed in the context of the most recent findings on PCB-induced endocrine-disrupting mechanisms and modes of action. PB - Elsevier T2 - Current Opinion in Toxicology T1 - Endocrine-disrupting mechanisms of polychlorinated biphenyls VL - 19 SP - 42 EP - 49 DO - 10.1016/j.cotox.2019.10.006 ER -
@article{ author = "Buha-Đorđević, Aleksandra and Antonijević, Evica and Ćurčić, Marijana and Milovanović, Vesna and Antonijević, Biljana", year = "2020", abstract = "The extent of human exposure to chemicals, their endocrine-disrupting mechanisms of action, and the relationship between exposure and various human diseases raise significant scientific and public health concerns. Polychlorinated biphenyls (PCBs) belong to the group of organic compounds known as persistent organic pollutants, characterized by long-range transport, persistence, bioaccumulation, and high toxicity. They have been identified as endocrine-disrupting chemicals. In vivo and in vitro studies have shown that endocrine-disrupting effects of PCBs mainly involve thyroid and reproductive function. In the review presented, these effects were placed in the context of the most recent findings on PCB-induced endocrine-disrupting mechanisms and modes of action.", publisher = "Elsevier", journal = "Current Opinion in Toxicology", title = "Endocrine-disrupting mechanisms of polychlorinated biphenyls", volume = "19", pages = "42-49", doi = "10.1016/j.cotox.2019.10.006" }
Buha-Đorđević, A., Antonijević, E., Ćurčić, M., Milovanović, V.,& Antonijević, B.. (2020). Endocrine-disrupting mechanisms of polychlorinated biphenyls. in Current Opinion in Toxicology Elsevier., 19, 42-49. https://doi.org/10.1016/j.cotox.2019.10.006
Buha-Đorđević A, Antonijević E, Ćurčić M, Milovanović V, Antonijević B. Endocrine-disrupting mechanisms of polychlorinated biphenyls. in Current Opinion in Toxicology. 2020;19:42-49. doi:10.1016/j.cotox.2019.10.006 .
Buha-Đorđević, Aleksandra, Antonijević, Evica, Ćurčić, Marijana, Milovanović, Vesna, Antonijević, Biljana, "Endocrine-disrupting mechanisms of polychlorinated biphenyls" in Current Opinion in Toxicology, 19 (2020):42-49, https://doi.org/10.1016/j.cotox.2019.10.006 . .