dc.creator | Lučić, Branka | |
dc.creator | Radulović, Dušanka | |
dc.creator | Vujić, Zorica | |
dc.creator | Agbaba, Danica | |
dc.date.accessioned | 2019-09-02T11:00:25Z | |
dc.date.available | 2019-09-02T11:00:25Z | |
dc.date.issued | 2005 | |
dc.identifier.issn | 0933-4173 | |
dc.identifier.uri | https://farfar.pharmacy.bg.ac.rs/handle/123456789/570 | |
dc.description.abstract | A method for chromatographic separation of the enantiomers of (+/-)-metoprolol tartrate (+/- MeT) employing a chiral mobile phase additive (CMPA) is described. By using silica gel plates previously impregnated with the mobile phase (ethanol-water, 70 + 30, v/v) containing D-(-)-tartaric acid as chiral selector, direct separation of the enantiomers of +/- MeT was achieved. The results of experiments with different concentrations of D-(-)-tartaric acid (5.8, 11.6, and 23 mmol L-1) revealed that the best resolution of the enantiomers of +/- MeT was achieved with 11.6 mm D-(-)-tartaric acid in both the mobile phase and the impregnation solution, at 25 2 degrees C. | en |
dc.publisher | Research Inst Medicinal Plants, Budakalasz | |
dc.rights | restrictedAccess | |
dc.source | Journal of Planar Chromatography - Modern TLC | |
dc.subject | TLC | en |
dc.subject | chiral separation | en |
dc.subject | metoprolol tartrate | en |
dc.subject | D-(-)-tartaric acid | en |
dc.title | Direct separation of the enantiomers of (+/-)-metoprolol tartrate on impregnated TLC plates with D-(-)-tartaric acid as a chiral selector | en |
dc.type | article | |
dc.rights.license | ARR | |
dcterms.abstract | Радуловић, Душанка; Лучић, Бранка; Вујић, Зорица; Aгбаба, Даница; | |
dc.citation.volume | 18 | |
dc.citation.issue | 104 | |
dc.citation.spage | 294 | |
dc.citation.epage | 299 | |
dc.citation.other | 18(104): 294-299 | |
dc.citation.rank | M23 | |
dc.identifier.wos | 000231689200008 | |
dc.identifier.doi | 10.1556/JPC.18.2005.4.8 | |
dc.identifier.scopus | 2-s2.0-24344454332 | |
dc.type.version | publishedVersion | |