Cytotoxicity in vitro of naphthazarin derivatives from Onosma arenaria
Abstract
The cytotoxicity of naphthazarin derivatives isolated from the roots of Onosma arenaria on human cervix adenocarcinoma cells (HeLa) and leukaemia K562 cells, as well on non-malignant peripheral blood mononuclear cells (PBMC) was studied. The results show that beta-hydroxyisovalerylalkannin, acetylalkannin and the pigment fraction exhibited high cytotoxicity in vitro against the tested cell lines, as well the healthy PBMC before or after activation with phytohaemagglutinin. Copyright
Keywords:
Onosma arenaria / cytotoxicity / acetylalkannin / beta-hydroxyisovalerylalkanninSource:
Phytotherapy Research, 2006, 20, 7, 602-604Publisher:
- John Wiley & Sons Ltd, Chichester
DOI: 10.1002/ptr.1899
ISSN: 0951-418X
PubMed: 16718737
WoS: 000239216900015
Scopus: 2-s2.0-33746002347
Collections
Institution/Community
PharmacyTY - JOUR AU - Kundaković, Tatjana AU - Stanojković, Tatjana AU - Juranić, Zorica AU - Kovačević, Nada PY - 2006 UR - https://farfar.pharmacy.bg.ac.rs/handle/123456789/813 AB - The cytotoxicity of naphthazarin derivatives isolated from the roots of Onosma arenaria on human cervix adenocarcinoma cells (HeLa) and leukaemia K562 cells, as well on non-malignant peripheral blood mononuclear cells (PBMC) was studied. The results show that beta-hydroxyisovalerylalkannin, acetylalkannin and the pigment fraction exhibited high cytotoxicity in vitro against the tested cell lines, as well the healthy PBMC before or after activation with phytohaemagglutinin. Copyright PB - John Wiley & Sons Ltd, Chichester T2 - Phytotherapy Research T1 - Cytotoxicity in vitro of naphthazarin derivatives from Onosma arenaria VL - 20 IS - 7 SP - 602 EP - 604 DO - 10.1002/ptr.1899 ER -
@article{ author = "Kundaković, Tatjana and Stanojković, Tatjana and Juranić, Zorica and Kovačević, Nada", year = "2006", abstract = "The cytotoxicity of naphthazarin derivatives isolated from the roots of Onosma arenaria on human cervix adenocarcinoma cells (HeLa) and leukaemia K562 cells, as well on non-malignant peripheral blood mononuclear cells (PBMC) was studied. The results show that beta-hydroxyisovalerylalkannin, acetylalkannin and the pigment fraction exhibited high cytotoxicity in vitro against the tested cell lines, as well the healthy PBMC before or after activation with phytohaemagglutinin. Copyright", publisher = "John Wiley & Sons Ltd, Chichester", journal = "Phytotherapy Research", title = "Cytotoxicity in vitro of naphthazarin derivatives from Onosma arenaria", volume = "20", number = "7", pages = "602-604", doi = "10.1002/ptr.1899" }
Kundaković, T., Stanojković, T., Juranić, Z.,& Kovačević, N.. (2006). Cytotoxicity in vitro of naphthazarin derivatives from Onosma arenaria. in Phytotherapy Research John Wiley & Sons Ltd, Chichester., 20(7), 602-604. https://doi.org/10.1002/ptr.1899
Kundaković T, Stanojković T, Juranić Z, Kovačević N. Cytotoxicity in vitro of naphthazarin derivatives from Onosma arenaria. in Phytotherapy Research. 2006;20(7):602-604. doi:10.1002/ptr.1899 .
Kundaković, Tatjana, Stanojković, Tatjana, Juranić, Zorica, Kovačević, Nada, "Cytotoxicity in vitro of naphthazarin derivatives from Onosma arenaria" in Phytotherapy Research, 20, no. 7 (2006):602-604, https://doi.org/10.1002/ptr.1899 . .