Synthesis, characterization, and biological activity of amino acid derivatives of the heteropolytungstophosphoric acid
Samo za registrovane korisnike
2006
Autori
Kuntić, VesnaStanojević, Maja
Holclajtner-Antunović, Ivanka
Uskoković-Marković, Snežana
Mioč, Ubavka B.
Todorović, Marija R.
Jovanović, Tanja
Vukojević, Vladana
Članak u časopisu (Objavljena verzija)
Metapodaci
Prikaz svih podataka o dokumentuApstrakt
Compounds of phosphotungstic acid (WPA) containing the amino acids alanine (WPA-Ala) or glycine (WPA-Gly) as counter cations were synthesized and characterized by elemental analysis, thermal analysis, and IR spectroscopy. Cellular toxicity was assessed by the trypan blue exclusion method, and the antiviral activity of WPA and the modified WPA compounds was tested against herpes simplex viruses (HSV) type 1 and type 2. Biological assays indicate that the newly synthesized compounds exhibit no evident cytotoxic effects on Vero cells and negligible antiviral activity against HSV-1 and HSV-2.
Ključne reči:
heteropoly compounds / amino acids / IR spectroscopy / cellular toxicity / antiviral activityIzvor:
Monatshefte für Chemie Chemical Monthly, 2006, 137, 6, 803-810Izdavač:
- Springer Wien, Wien
Finansiranje / projekti:
- Struktura, termodinamičke i elektrohemijske osobine materijala za konverziju energije i nove tehnologije (RS-142047)
- Supstance za farmaceutsku upotrebu: modeliranje, sinteza, fizičko-hemijske i biološke osobine, stepen čistoće i ispitivanje doziranih oblika (RS-142072)
DOI: 10.1007/s00706-006-0467-3
ISSN: 0026-9247
WoS: 000239791700012
Scopus: 2-s2.0-33745013371
Institucija/grupa
PharmacyTY - JOUR AU - Kuntić, Vesna AU - Stanojević, Maja AU - Holclajtner-Antunović, Ivanka AU - Uskoković-Marković, Snežana AU - Mioč, Ubavka B. AU - Todorović, Marija R. AU - Jovanović, Tanja AU - Vukojević, Vladana PY - 2006 UR - https://farfar.pharmacy.bg.ac.rs/handle/123456789/837 AB - Compounds of phosphotungstic acid (WPA) containing the amino acids alanine (WPA-Ala) or glycine (WPA-Gly) as counter cations were synthesized and characterized by elemental analysis, thermal analysis, and IR spectroscopy. Cellular toxicity was assessed by the trypan blue exclusion method, and the antiviral activity of WPA and the modified WPA compounds was tested against herpes simplex viruses (HSV) type 1 and type 2. Biological assays indicate that the newly synthesized compounds exhibit no evident cytotoxic effects on Vero cells and negligible antiviral activity against HSV-1 and HSV-2. PB - Springer Wien, Wien T2 - Monatshefte für Chemie Chemical Monthly T1 - Synthesis, characterization, and biological activity of amino acid derivatives of the heteropolytungstophosphoric acid VL - 137 IS - 6 SP - 803 EP - 810 DO - 10.1007/s00706-006-0467-3 ER -
@article{ author = "Kuntić, Vesna and Stanojević, Maja and Holclajtner-Antunović, Ivanka and Uskoković-Marković, Snežana and Mioč, Ubavka B. and Todorović, Marija R. and Jovanović, Tanja and Vukojević, Vladana", year = "2006", abstract = "Compounds of phosphotungstic acid (WPA) containing the amino acids alanine (WPA-Ala) or glycine (WPA-Gly) as counter cations were synthesized and characterized by elemental analysis, thermal analysis, and IR spectroscopy. Cellular toxicity was assessed by the trypan blue exclusion method, and the antiviral activity of WPA and the modified WPA compounds was tested against herpes simplex viruses (HSV) type 1 and type 2. Biological assays indicate that the newly synthesized compounds exhibit no evident cytotoxic effects on Vero cells and negligible antiviral activity against HSV-1 and HSV-2.", publisher = "Springer Wien, Wien", journal = "Monatshefte für Chemie Chemical Monthly", title = "Synthesis, characterization, and biological activity of amino acid derivatives of the heteropolytungstophosphoric acid", volume = "137", number = "6", pages = "803-810", doi = "10.1007/s00706-006-0467-3" }
Kuntić, V., Stanojević, M., Holclajtner-Antunović, I., Uskoković-Marković, S., Mioč, U. B., Todorović, M. R., Jovanović, T.,& Vukojević, V.. (2006). Synthesis, characterization, and biological activity of amino acid derivatives of the heteropolytungstophosphoric acid. in Monatshefte für Chemie Chemical Monthly Springer Wien, Wien., 137(6), 803-810. https://doi.org/10.1007/s00706-006-0467-3
Kuntić V, Stanojević M, Holclajtner-Antunović I, Uskoković-Marković S, Mioč UB, Todorović MR, Jovanović T, Vukojević V. Synthesis, characterization, and biological activity of amino acid derivatives of the heteropolytungstophosphoric acid. in Monatshefte für Chemie Chemical Monthly. 2006;137(6):803-810. doi:10.1007/s00706-006-0467-3 .
Kuntić, Vesna, Stanojević, Maja, Holclajtner-Antunović, Ivanka, Uskoković-Marković, Snežana, Mioč, Ubavka B., Todorović, Marija R., Jovanović, Tanja, Vukojević, Vladana, "Synthesis, characterization, and biological activity of amino acid derivatives of the heteropolytungstophosphoric acid" in Monatshefte für Chemie Chemical Monthly, 137, no. 6 (2006):803-810, https://doi.org/10.1007/s00706-006-0467-3 . .