Antioxidant activity of four endemic Stachys taxa
Apstrakt
Methanol extracts of aerial flowering parts of four endemic Stachys taxa: S. anisochila Vis. et PANCIC, S. beckeana DORFLER & HAYEK, S. plumosa GRISEB. and S. alpina L. ssp. dinarica MURB. were investigated on their antioxidant activity. The extracts were studied for total antioxidant activity (TAA), along with 1,1-diphenyl 2-picryl hydrazyl (DPPH) and OH radical scavenging activity, and lipid peroxidation (LP). High correlations between total phenolics content, TAA and scavenging DPPH radical indicate that polyphenols are the main antioxidants. All Stachys extracts, with the exception of S. plumosa, exhibited high anti-DPPH activity (IC50 lt 50 mu g/ml). In concentration range from 6.25 to 50 mu g/ml, all extracts scavenged OH radical above 40%, with maximal inhibitions for S. anisochila, S. alpina ssp. dinarica and S. beckeana extracts of 50.22%, 50.94% and 64.97%, respectively. Only S. plumosa extract achieved maximal activity of 60.67% at 100 mu g/ml. As for LP, IC50 values for S.... beckeana and S. alpina ssp. dinarica extracts were 25.07 and 49.00 mu g/ml, respectively, while S. anisochila and S. plumosa extracts did not reach 50% of LP inhibition.
Ključne reči:
Stachys / polyphenol / antioxidant activity / 1,1-diphenyl 2-picryl hydrazyl (DPPH) / hydroxyl radical / lipid peroxidationIzvor:
Biological & Pharmaceutical Bulletin, 2006, 29, 4, 725-729Izdavač:
- Pharmaceutical Soc Japan, Tokyo
DOI: 10.1248/bpb.29.725
ISSN: 0918-6158
PubMed: 16595907
WoS: 000237310700022
Scopus: 2-s2.0-33645552916
Institucija/grupa
PharmacyTY - JOUR AU - Kukić, Jelena AU - Petrović, Silvana AU - Niketić, Marjan PY - 2006 UR - https://farfar.pharmacy.bg.ac.rs/handle/123456789/865 AB - Methanol extracts of aerial flowering parts of four endemic Stachys taxa: S. anisochila Vis. et PANCIC, S. beckeana DORFLER & HAYEK, S. plumosa GRISEB. and S. alpina L. ssp. dinarica MURB. were investigated on their antioxidant activity. The extracts were studied for total antioxidant activity (TAA), along with 1,1-diphenyl 2-picryl hydrazyl (DPPH) and OH radical scavenging activity, and lipid peroxidation (LP). High correlations between total phenolics content, TAA and scavenging DPPH radical indicate that polyphenols are the main antioxidants. All Stachys extracts, with the exception of S. plumosa, exhibited high anti-DPPH activity (IC50 lt 50 mu g/ml). In concentration range from 6.25 to 50 mu g/ml, all extracts scavenged OH radical above 40%, with maximal inhibitions for S. anisochila, S. alpina ssp. dinarica and S. beckeana extracts of 50.22%, 50.94% and 64.97%, respectively. Only S. plumosa extract achieved maximal activity of 60.67% at 100 mu g/ml. As for LP, IC50 values for S. beckeana and S. alpina ssp. dinarica extracts were 25.07 and 49.00 mu g/ml, respectively, while S. anisochila and S. plumosa extracts did not reach 50% of LP inhibition. PB - Pharmaceutical Soc Japan, Tokyo T2 - Biological & Pharmaceutical Bulletin T1 - Antioxidant activity of four endemic Stachys taxa VL - 29 IS - 4 SP - 725 EP - 729 DO - 10.1248/bpb.29.725 ER -
@article{ author = "Kukić, Jelena and Petrović, Silvana and Niketić, Marjan", year = "2006", abstract = "Methanol extracts of aerial flowering parts of four endemic Stachys taxa: S. anisochila Vis. et PANCIC, S. beckeana DORFLER & HAYEK, S. plumosa GRISEB. and S. alpina L. ssp. dinarica MURB. were investigated on their antioxidant activity. The extracts were studied for total antioxidant activity (TAA), along with 1,1-diphenyl 2-picryl hydrazyl (DPPH) and OH radical scavenging activity, and lipid peroxidation (LP). High correlations between total phenolics content, TAA and scavenging DPPH radical indicate that polyphenols are the main antioxidants. All Stachys extracts, with the exception of S. plumosa, exhibited high anti-DPPH activity (IC50 lt 50 mu g/ml). In concentration range from 6.25 to 50 mu g/ml, all extracts scavenged OH radical above 40%, with maximal inhibitions for S. anisochila, S. alpina ssp. dinarica and S. beckeana extracts of 50.22%, 50.94% and 64.97%, respectively. Only S. plumosa extract achieved maximal activity of 60.67% at 100 mu g/ml. As for LP, IC50 values for S. beckeana and S. alpina ssp. dinarica extracts were 25.07 and 49.00 mu g/ml, respectively, while S. anisochila and S. plumosa extracts did not reach 50% of LP inhibition.", publisher = "Pharmaceutical Soc Japan, Tokyo", journal = "Biological & Pharmaceutical Bulletin", title = "Antioxidant activity of four endemic Stachys taxa", volume = "29", number = "4", pages = "725-729", doi = "10.1248/bpb.29.725" }
Kukić, J., Petrović, S.,& Niketić, M.. (2006). Antioxidant activity of four endemic Stachys taxa. in Biological & Pharmaceutical Bulletin Pharmaceutical Soc Japan, Tokyo., 29(4), 725-729. https://doi.org/10.1248/bpb.29.725
Kukić J, Petrović S, Niketić M. Antioxidant activity of four endemic Stachys taxa. in Biological & Pharmaceutical Bulletin. 2006;29(4):725-729. doi:10.1248/bpb.29.725 .
Kukić, Jelena, Petrović, Silvana, Niketić, Marjan, "Antioxidant activity of four endemic Stachys taxa" in Biological & Pharmaceutical Bulletin, 29, no. 4 (2006):725-729, https://doi.org/10.1248/bpb.29.725 . .