The dry plant extract of common bean seed (Phaseoli vulgari pericarpium) does not have an affect on postprandial glycemia in healthy human subject.
Нема приказа
Аутори
Cerović, AleksandraMiletić, Ivanka
Konić-Ristić, Aleksandra
Baralić, Ivana
Đorđević, Brižita
Đuričić, Ivana
Radusinović, M
Чланак у часопису (Објављена верзија)
Метаподаци
Приказ свих података о документуАпстракт
The aim of present study was to assess the effects and safety of a dry Phaseoli vulgari pericarpium (PVP) extract on postprandial glycemia in healthy participants. A randomized crossover experiment where participants received either PVP extract or placebo. Chemical compounds in dry extract were assessed by established methods. Eighteen healthy participants (9 male and 9 female) aged 29+/-4,8 years, body mass index (BMI) 23+/-3,7 kg/m(2) were recruited among students and staff at the Faculty of Pharmacy, University of Belgrade. All participants were able to follow the study protocol without difficulty. The participants received either PVP extract or placebo 30 minutes before a 50g oral glucose tolerance test (OGTT). The protocol followed the guidelines for the OGTT with blood samples drawn at 0, 15, 30, 60, 90 and 120 min. This study demonstrated that there was no significantly effect of the PVP extract on incremental blood glucose (IBG) and their areas under the curve (AUC) neither mal...e nor female participants. However, IBG together with AUC changes were significantly lower in male compared with female participants in treated and untreated groups. The presence of chrome, soluble fiber, vitamin C, protein, glucose and lectins were also quantified. The applied amount of PVP extract was unable to produce the postprandial hypoglycemia. We assumed that amounts of chrome, soluble fiber, vitamin C which have beneficial effects on diabetes treatment were sufficient to produce hypoglycemia.
Извор:
Bosnian Journal of Basic Medical Sciences, 2006, 6, 3, 28-33Издавач:
- Association of Basic Medical Sciences of Federation of Bosnia and Herzegovina
Институција/група
PharmacyTY - JOUR AU - Cerović, Aleksandra AU - Miletić, Ivanka AU - Konić-Ristić, Aleksandra AU - Baralić, Ivana AU - Đorđević, Brižita AU - Đuričić, Ivana AU - Radusinović, M PY - 2006 UR - https://farfar.pharmacy.bg.ac.rs/handle/123456789/869 AB - The aim of present study was to assess the effects and safety of a dry Phaseoli vulgari pericarpium (PVP) extract on postprandial glycemia in healthy participants. A randomized crossover experiment where participants received either PVP extract or placebo. Chemical compounds in dry extract were assessed by established methods. Eighteen healthy participants (9 male and 9 female) aged 29+/-4,8 years, body mass index (BMI) 23+/-3,7 kg/m(2) were recruited among students and staff at the Faculty of Pharmacy, University of Belgrade. All participants were able to follow the study protocol without difficulty. The participants received either PVP extract or placebo 30 minutes before a 50g oral glucose tolerance test (OGTT). The protocol followed the guidelines for the OGTT with blood samples drawn at 0, 15, 30, 60, 90 and 120 min. This study demonstrated that there was no significantly effect of the PVP extract on incremental blood glucose (IBG) and their areas under the curve (AUC) neither male nor female participants. However, IBG together with AUC changes were significantly lower in male compared with female participants in treated and untreated groups. The presence of chrome, soluble fiber, vitamin C, protein, glucose and lectins were also quantified. The applied amount of PVP extract was unable to produce the postprandial hypoglycemia. We assumed that amounts of chrome, soluble fiber, vitamin C which have beneficial effects on diabetes treatment were sufficient to produce hypoglycemia. PB - Association of Basic Medical Sciences of Federation of Bosnia and Herzegovina T2 - Bosnian Journal of Basic Medical Sciences T1 - The dry plant extract of common bean seed (Phaseoli vulgari pericarpium) does not have an affect on postprandial glycemia in healthy human subject. VL - 6 IS - 3 SP - 28 EP - 33 UR - https://hdl.handle.net/21.15107/rcub_farfar_869 ER -
@article{ author = "Cerović, Aleksandra and Miletić, Ivanka and Konić-Ristić, Aleksandra and Baralić, Ivana and Đorđević, Brižita and Đuričić, Ivana and Radusinović, M", year = "2006", abstract = "The aim of present study was to assess the effects and safety of a dry Phaseoli vulgari pericarpium (PVP) extract on postprandial glycemia in healthy participants. A randomized crossover experiment where participants received either PVP extract or placebo. Chemical compounds in dry extract were assessed by established methods. Eighteen healthy participants (9 male and 9 female) aged 29+/-4,8 years, body mass index (BMI) 23+/-3,7 kg/m(2) were recruited among students and staff at the Faculty of Pharmacy, University of Belgrade. All participants were able to follow the study protocol without difficulty. The participants received either PVP extract or placebo 30 minutes before a 50g oral glucose tolerance test (OGTT). The protocol followed the guidelines for the OGTT with blood samples drawn at 0, 15, 30, 60, 90 and 120 min. This study demonstrated that there was no significantly effect of the PVP extract on incremental blood glucose (IBG) and their areas under the curve (AUC) neither male nor female participants. However, IBG together with AUC changes were significantly lower in male compared with female participants in treated and untreated groups. The presence of chrome, soluble fiber, vitamin C, protein, glucose and lectins were also quantified. The applied amount of PVP extract was unable to produce the postprandial hypoglycemia. We assumed that amounts of chrome, soluble fiber, vitamin C which have beneficial effects on diabetes treatment were sufficient to produce hypoglycemia.", publisher = "Association of Basic Medical Sciences of Federation of Bosnia and Herzegovina", journal = "Bosnian Journal of Basic Medical Sciences", title = "The dry plant extract of common bean seed (Phaseoli vulgari pericarpium) does not have an affect on postprandial glycemia in healthy human subject.", volume = "6", number = "3", pages = "28-33", url = "https://hdl.handle.net/21.15107/rcub_farfar_869" }
Cerović, A., Miletić, I., Konić-Ristić, A., Baralić, I., Đorđević, B., Đuričić, I.,& Radusinović, M.. (2006). The dry plant extract of common bean seed (Phaseoli vulgari pericarpium) does not have an affect on postprandial glycemia in healthy human subject.. in Bosnian Journal of Basic Medical Sciences Association of Basic Medical Sciences of Federation of Bosnia and Herzegovina., 6(3), 28-33. https://hdl.handle.net/21.15107/rcub_farfar_869
Cerović A, Miletić I, Konić-Ristić A, Baralić I, Đorđević B, Đuričić I, Radusinović M. The dry plant extract of common bean seed (Phaseoli vulgari pericarpium) does not have an affect on postprandial glycemia in healthy human subject.. in Bosnian Journal of Basic Medical Sciences. 2006;6(3):28-33. https://hdl.handle.net/21.15107/rcub_farfar_869 .
Cerović, Aleksandra, Miletić, Ivanka, Konić-Ristić, Aleksandra, Baralić, Ivana, Đorđević, Brižita, Đuričić, Ivana, Radusinović, M, "The dry plant extract of common bean seed (Phaseoli vulgari pericarpium) does not have an affect on postprandial glycemia in healthy human subject." in Bosnian Journal of Basic Medical Sciences, 6, no. 3 (2006):28-33, https://hdl.handle.net/21.15107/rcub_farfar_869 .