Compounds of Mo, V and W in biochemistry and their biomedical activity
Samo za registrovane korisnike
2007
Autori
Jelikić-Stankov, MilenaUskoković-Marković, Snežana
Holclajtner-Antunović, Ivanka
Todorović, Marija R.
Đurđević, Predrag
Članak u časopisu (Objavljena verzija)
Metapodaci
Prikaz svih podataka o dokumentuApstrakt
Molybdenum, vanadium and tungsten compounds are widely applied as analytical reagents for determination of numerous pharmacologically active substances and different biochemical parameters. Recent data from the available literature pointed to a very potent biomedical activity of compounds containing these trace elements. The present paper represents a survey on the structure and chemical properties of these compounds, as well as on their biological activity, mostly based on their interaction with cations of biomolecules, such as phospholipids and proteins. Besides, their potent inhibitory effects on cellular targets, bacterial and viral DNA and RNA polymerases will be discussed, as well. Numerous authors clearly demonstrated the antiviral (especially anti-HIV), anticoagulant and antineoplastic properties of the compounds containing the above trace elements. It has been also shown that these compounds act on some cellular enzymatic systems leading to the normalisation of blood pressure,... blood glucose and serum lipid levels. Also, compounds of these trace elements represent potent antiobesity agents and express hepatoprotective and antioxidative stress activity.
Ključne reči:
molybdenum / vanadium / tungsten / biomedical activityIzvor:
Journal of Trace Elements in Medicine and Biology, 2007, 21, 1, 8-16Izdavač:
- Elsevier Gmbh, Urban & Fischer Verlag, Jena
Finansiranje / projekti:
- Bioaktivni kompleksi p i d jona metala sa ligandima farmakoterapijskog značaja (RS-142013)
- Struktura, termodinamičke i elektrohemijske osobine materijala za konverziju energije i nove tehnologije (RS-142047)
DOI: 10.1016/j.jtemb.2006.11.004
ISSN: 0946-672X
PubMed: 17317520
WoS: 000245350300002
Scopus: 2-s2.0-33847195018
Institucija/grupa
PharmacyTY - JOUR AU - Jelikić-Stankov, Milena AU - Uskoković-Marković, Snežana AU - Holclajtner-Antunović, Ivanka AU - Todorović, Marija R. AU - Đurđević, Predrag PY - 2007 UR - https://farfar.pharmacy.bg.ac.rs/handle/123456789/912 AB - Molybdenum, vanadium and tungsten compounds are widely applied as analytical reagents for determination of numerous pharmacologically active substances and different biochemical parameters. Recent data from the available literature pointed to a very potent biomedical activity of compounds containing these trace elements. The present paper represents a survey on the structure and chemical properties of these compounds, as well as on their biological activity, mostly based on their interaction with cations of biomolecules, such as phospholipids and proteins. Besides, their potent inhibitory effects on cellular targets, bacterial and viral DNA and RNA polymerases will be discussed, as well. Numerous authors clearly demonstrated the antiviral (especially anti-HIV), anticoagulant and antineoplastic properties of the compounds containing the above trace elements. It has been also shown that these compounds act on some cellular enzymatic systems leading to the normalisation of blood pressure, blood glucose and serum lipid levels. Also, compounds of these trace elements represent potent antiobesity agents and express hepatoprotective and antioxidative stress activity. PB - Elsevier Gmbh, Urban & Fischer Verlag, Jena T2 - Journal of Trace Elements in Medicine and Biology T1 - Compounds of Mo, V and W in biochemistry and their biomedical activity VL - 21 IS - 1 SP - 8 EP - 16 DO - 10.1016/j.jtemb.2006.11.004 ER -
@article{ author = "Jelikić-Stankov, Milena and Uskoković-Marković, Snežana and Holclajtner-Antunović, Ivanka and Todorović, Marija R. and Đurđević, Predrag", year = "2007", abstract = "Molybdenum, vanadium and tungsten compounds are widely applied as analytical reagents for determination of numerous pharmacologically active substances and different biochemical parameters. Recent data from the available literature pointed to a very potent biomedical activity of compounds containing these trace elements. The present paper represents a survey on the structure and chemical properties of these compounds, as well as on their biological activity, mostly based on their interaction with cations of biomolecules, such as phospholipids and proteins. Besides, their potent inhibitory effects on cellular targets, bacterial and viral DNA and RNA polymerases will be discussed, as well. Numerous authors clearly demonstrated the antiviral (especially anti-HIV), anticoagulant and antineoplastic properties of the compounds containing the above trace elements. It has been also shown that these compounds act on some cellular enzymatic systems leading to the normalisation of blood pressure, blood glucose and serum lipid levels. Also, compounds of these trace elements represent potent antiobesity agents and express hepatoprotective and antioxidative stress activity.", publisher = "Elsevier Gmbh, Urban & Fischer Verlag, Jena", journal = "Journal of Trace Elements in Medicine and Biology", title = "Compounds of Mo, V and W in biochemistry and their biomedical activity", volume = "21", number = "1", pages = "8-16", doi = "10.1016/j.jtemb.2006.11.004" }
Jelikić-Stankov, M., Uskoković-Marković, S., Holclajtner-Antunović, I., Todorović, M. R.,& Đurđević, P.. (2007). Compounds of Mo, V and W in biochemistry and their biomedical activity. in Journal of Trace Elements in Medicine and Biology Elsevier Gmbh, Urban & Fischer Verlag, Jena., 21(1), 8-16. https://doi.org/10.1016/j.jtemb.2006.11.004
Jelikić-Stankov M, Uskoković-Marković S, Holclajtner-Antunović I, Todorović MR, Đurđević P. Compounds of Mo, V and W in biochemistry and their biomedical activity. in Journal of Trace Elements in Medicine and Biology. 2007;21(1):8-16. doi:10.1016/j.jtemb.2006.11.004 .
Jelikić-Stankov, Milena, Uskoković-Marković, Snežana, Holclajtner-Antunović, Ivanka, Todorović, Marija R., Đurđević, Predrag, "Compounds of Mo, V and W in biochemistry and their biomedical activity" in Journal of Trace Elements in Medicine and Biology, 21, no. 1 (2007):8-16, https://doi.org/10.1016/j.jtemb.2006.11.004 . .