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Prediction of aqueous solubility of drug-like molecules using a novel algorithm for automatic adjustment of relative importance of descriptors implemented in counter-propagation artificial neural networks
(Elsevier Science BV, Amsterdam, 2012)
In this work, we present a novel approach for the development of models for prediction of aqueous solubility, based on the implementation of an algorithm for the automatic adjustment of descriptor's relative importance ...
Pharmacokinetics of erythropoietin in Balkan endemic nephropathy patients
(Oxford Univ Press, Oxford, 2012)
Bioactivity assays on Carlina acaulis and C. acanthifolia root and herb extracts
(Inst Materials Physics, Bucharest, 2012)
The present study describes investigation on chemical profile and pharmacological properties of hydromethanolic extracts of Carlina acaulis and C. acanthifolia roots and herbs. In order to investigate the antioxidant ...
The Local Peripheral Antihyperalgesic Effect of Levetiracetam and Its Mechanism of Action in an Inflammatory Pain Model
(Lippincott Williams & Wilkins, Philadelphia, 2012)
BACKGROUND: We have recently shown that levetiracetam, administered systemically, exerts an antihyperalgesic effect in a rat inflammatory pain model. In this study, we examined whether levetiracetam has local peripheral ...
Occupational stress and burnout: impact on the attitudes of pharmacists in providing pharmaceutical services
(Elsevier Science Inc, 2012)
OBJECTIVES: To determine the relationship between occupational stress and burn-
out of pharmacists in community pharmacies as well as the influence on the phar-
macists’ attitudes about their own work with patients. ...
Target fishing and docking studies of the novel derivatives of aryl-aminopyridines with potential anticancer activity
(Pergamon-Elsevier Science Ltd, Oxford, 2012)
A set of 16 previously synthesized aryl-aminopyridine and aryl-aminoquinoline derivatives have been evaluated for cytotoxic activity against three cancer cell lines (human cervical cancer-HeLa; human chronic myeloid ...