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Приказ резултата 1-10 од 301
Optimization of formulation and process parameters for the production of carvedilol nanosuspension by wet media milling
(Elsevier Science BV, Amsterdam, 2018)
The aim of this study is to develop nanosuspension of carvedilol (CRV) by wet media milling. Concentration of polymeric stabilizer (hydroxypropyl cellulose-HPC-SL), milling speed and size of milling beads were identified ...
Effect assessment of target tissue doses of cadmium and decabrominated diphenyl ether on GSH level in kidneys
(Elsevier Ireland Ltd, Clare, 2018)
Semisolid self-microemulsifying drug delivery systems (SMEDDSs): Effects on pharmacokinetics of acyclovir in rats
(Elsevier Science BV, Amsterdam, 2018)
Semisolid self-microemulsifying drug delivery system (SMEDDS) with optimized drug loading capacity, stability, dispersibility in aqueous media and in vitro drug release profile, was evaluated in vivo regarding effects on ...
In vitro/in silico approach in the development of simvastatin-loaded self-microemulsifying drug delivery systems
(Taylor & Francis Ltd, Abingdon, 2018)
Objective: The aims of this study were to formulate simvastatin (SV)-loaded self-microemulsifying drug delivery systems (SMEDDS), and explore the potential of these drug delivery systems to improve SV solubility, and also ...
Antiepileptic drugs as analgesics/adjuvants in inflammatory pain: current preclinical evidence
(Pergamon-Elsevier Science Ltd, Oxford, 2018)
Inflammatory pain is the most common type of pain that is treated clinically. The use of currently available treatments (classic analgesics - NSAID5, paracetamol and opioids) is limited by insufficient efficacy and/or side ...
A single dose of magnesium, as well as chronic administration, enhances long-term memory in novel object recognition test, in healthy and ACTH-treated rats
(John Libbey Eurotext Ltd, Montrouge, 2018)
Although a magnesium-mediated attenuation of memory deficits was reported in animal models of ageing and traumatic brain injury, a possible memory enhancement in healthy subjects has not been investigated yet. We used novel ...
An investigation into the effects of excipients on quality characteristics of a dry herbal extract containing capsule
(Savez hemijskih inženjera, Beograd, 2018)
Nutrition and dietary supplements have a significant role in the prevention and treatment of cardiovascular disease. Olive and vine leaves, thanks to their constituents, represent powerful natural antioxidants exhibiting ...
Cardiovascular risk assessed by reynolds risk score in relation to waist circumference in apparently healthy middle-aged population in Montenegro
(Sestre Milosrdnice Univ Hospital, Zagreb, 2018)
Reynolds Risk Score (RRS) is regarded as a good screening tool for cardiovascular disease (CVD) risk. Since CVD is the leading cause of death in Montenegro, we aimed to assess the risk of CVD as assessed by RRS and to ...
Are visceral adiposity index and lipid accumulation product reliable indices for metabolic disturbances in patients with type 2 diabetes mellitus?
(Wiley, Hoboken, 2018)
BackgroundVisceral adiposity index (VAI) and Lipid accumulation product (LAP) are novel visceral adiposity indexes, proposed for the evaluation of cardiometabolic risk in adult population. Considering contradictory results ...
Ispitivanje antioksidativnog i antimikrobnog potencijala kakao praha i njegovog uticaja na ponašanje miševa nakon kratkotrajne i dugotrajne suplementacije
(Универзитет у Београду, Фармацеутски факултет, 2018)
Kakao prah je industrijski proizvod koji se dobija preradom kakao zrna (Theobroma cacao L.) i poseduje jedinstven ukus i aromu. Sve češće se svrstava u veoma popularnu grupu „funkcionalnih namirnica“. Visok sadržaj biološki ...