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Acid-base equilibria and solubility of loratadine and desloratadine in water and micellar media
(Pergamon-Elsevier Science Ltd, Oxford, 2009)
Acid-base equilibria in homogeneous and heterogeneous systems of two antihistaminics, loratadine and desloratadine were studied spectrophotometrically in Britton-Robinson's buffer at 25 degrees C. Acidity constant of ...
Trace elements analysis of Echinacea purpurea - herbal medicinal
(Elsevier Science BV, Amsterdam, 2003)
Elemental composition of Echinacea purpurea (Asteracae), grown in Serbia under strongly controlled conditions, has been studied. To distinguish elemental patterns of different parts of the plant, the content of Zn, Fe, Cu, ...
Study of forced degradation behavior of Eletriptan hydrobromide by LC and LC-MS and development of stability-indicating method
(Elsevier Science BV, Amsterdam, 2009)
The objective of the present study was to report the stability profile of novel antimigrain drug Eletriptan hydrobromide based on the information obtained from forced degradation studies. The drug was subjected to acid ...
Multicriteria optimization methodology in development of HPLC separation of mycophenolic acid and mycophenolic acid glucuronide in human urine and plasma
(Elsevier Science BV, Amsterdam, 2009)
Multicriteria optimization methodology was applied for development of isocratic reversed-phased HPLC method for simultaneous determination of mycophenolic acid (MPA) and mycophenolic acid glucuronide (MPAG) in human urine ...
Spectrophotometric determination of obidoxime chloride as its Pd(II) complex in water and injections
(Journal of Pharmaceutical and Biomedical Analysis, 1987)
It has been established that obidoxime chloride reacts with palladium(II) chloride in the pH range 3.9-8.0 and forms a yellow water-soluble (1:1) complex with maximum absorbance at 355 nm. By applying the methods of Sommer, ...
Determination of paracetamol in pure and pharmaceutical dosage forms by pulse perturbation technique
(Elsevier Science BV, Amsterdam, 2006)
A new procedure for kinetic determination of paracetamol in pharmaceuticals is proposed. The method is based on potentiometric monitoring of the concentration perturbations of the matrix reaction system being in a stable ...
Photochemical degradation of solid-state nisoldipine monitored by HPLC
(Pergamon-Elsevier Science Ltd, Oxford, 2003)
The photochemical degradation of solid-state nisoldipine, 1,4-dihydropyridine calcium antagonist, was investigated under daylight and UV light conditions. Degradation products were identified by using the retention times ...
Use of palladium(II) chloride as colour-forming reagent in determination of pralidoxime chloride in water and tablets
(Journal of Pharmaceutical and Biomedical Analysis, 1988)
Pralidoxime chloride (PAM-2Cl) has been determined spectrophotometrically in Britton-Robinson buffer solution at pH = 6.45; the method is based on measurement of the absorbance of the Pd(II)-pralidoxime complex at 327 nm. ...
HPTLC determination of ceftriaxone, cefixime and cefotaxime in dosage forms
(Pergamon-Elsevier Science Ltd, Oxford, 1998)
The objective of this investigation was to develop a HPTLC method for the determination of ceftriaxone, cefixime and cefotaxime, cephalosporins widely used in clinical practice, High performance TLC of cephalosporins was ...
Determination of fleroxacin in human serum and in dosage forms by derivative UV spectrophotometry
(Pergamon-Elsevier Science Ltd, Oxford, 1998)