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An investigation into applicability of sodium carboxymethylcellulose and sodium alginate as film-forming agents for semi-solid 3D printing
(Macedonian Pharmaceutical AssociationSs. Cyril and Methodius University in Skopje, Faculty of Pharmacy, 2023)
Semi-solid 3D printing technology has gained
increased interest in the pharmaceutical field as it enables
on-demand fabrication of personalized dosage forms.
Orodispersible films (ODFs) are good candidates for 3D
printing ...
The influence of preparation conditions on the formation and extent of interactions in chitosan/xanthan gum polyelectrolyte complexes as potential drug delivery carriers
(Macedonian Pharmaceutical AssociationSs. Cyril and Methodius University in Skopje, Faculty of Pharmacy, 2023)
The formation and properties of polyelectrolyte
complexes (PECs) based on chitosan (CH) and xanthan
gum (XG) depend on various preparation parameters (pH
value, ionic strength, mixing order of polyelectrolytes,
etc.). ...
Preformulation and development of preliminary nanoemulsion carrier for patent protected compound GL-II-73
(Macedonian Pharmaceutical AssociationSs. Cyril and Methodius University in Skopje, Faculty of Pharmacy, 2023)
Nanopharmaceuticals offer a good option to avoid
some of the difficulties that novel drug candidates
confront. They can be tailored to adjust their water
solubility, half-life, biodistribution, and govern the release
of ...
In silico assessment of intestinal precipitation: Case study of a poorly soluble, weakly basic compound
(Macedonian Pharmaceutical AssociationSs. Cyril and Methodius University in Skopje, Faculty of Pharmacy, 2023)
Precipitation of a drug substance in the small intestine
is a phenomenon relevant to weak bases due to their pH-
dependent solubility. Because of the low solubility at
higher pH, upon entry in the small intestine, a ...
Data mining implementation in multiparticulate unit systems characterization
(Macedonian Pharmaceutical AssociationSs. Cyril and Methodius University in Skopje, Faculty of Pharmacy, 2023)
Multiparticulate unit systems (MPUs) represent
versatile drug delivery systems which provide flexible
dosing and reproducible drug release profile (Al-Hashimi
et al., 2018). They are usually filled in capsules/sachets ...
Anatomical characterization, chemical analyses and essential oil antimicrobial activity of Hyssopus officinalis L. (Lamiaceae)
(Macedonian Pharmaceutical AssociationSs. Cyril and Methodius University in Skopje, Faculty of Pharmacy, 2022)
Introduction
Hyssopus officinalis L. (Lamiaceae) is a perennial aromatic subshrub, distributed mainly in the Mediterranean area. The aerial parts of the plant are used as a culinary and medicinal herb (Hyssopi herba) ...
Applicability of Expert System for Drug Development as a tool for co-processed excipients formulation development
(Macedonian Pharmaceutical AssociationFaculty of Pharmacy, Ss Cyril and Methodius University in Skopje, 2022)
Expert System for Drug Development, i.e. SeDeM
Expert System (Span. Sistema Experto para DEsarrollo
de Medicamentos) represents a method intended for
evaluation of powder properties affecting processability,
particularly ...
Pharmaceutical and technological characteristics of barium sulphate tablets -the screening of various formulation factors
(Macedonian Pharmaceutical AssociationFaculty of Pharmacy, Ss Cyril and Methodius University in Skopje, 2022)
Introduction The study examined the development of barium sulphate tablets that do not dissolve in the digestive tract
and are used as a contrasting agent for measuring transit time through the column. The main problem ...
Application of the Gradient boosted tree approach for thin film classification based on disintegration time
(Macedonian Pharmaceutical AssociationSs. Cyril and Methodius University in Skopje, Faculty of Pharmacy, 2023)
Thin films are polymeric strips that disintegrate in the
oral cavity and consist of a film-forming agent and an
active pharmaceutical ingredient (API). Generally, thin
films disintegrate within seconds, but their ...
Fun-shaped oral dosage forms for the pediatric population fabricated by digital light processing (DLP) 3D printing technique
(Macedonian Pharmaceutical AssociationFaculty of Pharmacy, Ss Cyril and Methodius University in Skopje, 2022)
Introduction Three-dimensional (3D) printing as an innovative technology in the field of drug manufacturing has attracted a lot of attention from the scientific and professional public in recent years. Classified into seven ...