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Generic approach in a gradient elution HPLC method development that enables troubleshooting free method transfer
(Elsevier B.V., 2022)
Nowadays, method development is strongly focused on reducing time needed for method development and execution. This subject specially concerns gradient elution methods regarding the usual need for trouble shooting assistance ...
Grape Seed Oil Characterization: A Novel Approach for Oil Quality Assessment
(Wiley-VCH Verlag, 2020)
The amount of organic pomace, left behind agricultural processes, is continuously rising in accordance with industrial progress. Grape pomace, generated in the wine industry all over the world, represents a raw material ...
Effect of small changes in natural origin-based emulsion systems on hydrocortisone skin absorption and performance: a comparison of two in vivo methods
(Taylor & Francis Ltd, Abingdon, 2014)
Context: Alkyl polyglucoside surfactants (APG) remain prominent natural origin stabilizers offering a prospect of combining satisfactory stability with mild dermatological properties and complete biodegradability. Objective: ...
Ring closing metathesis/fragmentation route to (Z)-configured medium ring cycloalkenes. Total synthesis of (+/-)-periplanone C
(Amer Chemical Soc, Washington, 2006)
The combination of ring closing metathesis and beta-fragmentation offers an efficient entry into (Z)-configured medium ring cycloalkenes. The fragmentation step can be effected under anionic or radical conditions. The ...
Pyrrolidine derived thioureas as organocatalysts in the Michael reaction of vinyl sulfone. Structure-stereoselectivity study
(Pergamon-Elsevier Science Ltd, Oxford, 2016)
Structural variations of the heterocyclic ring of the recently introduced pyrrolidine derived thiourea organocatalysts have been studied. The results showed that the stereoselectivity is highly dependent on the substitution ...
Quantitative structure-retention relationship of selected imidazoline derivatives on alpha(1)-acid glycoprotein column
(Elsevier Science BV, Amsterdam, 2016)
The retention behaviour of 22 selected imidazoline drugs and derivatives was investigated on alpha(1)-acid glycoprotein (AGP) column using Sorensen phosphate buffer (pH 7.0) and 2-propanol as organic modifier. Quantitative ...
Tailored porosity development in carbons via Zn2+ monodispersion: Fitting supercapacitors
(Elsevier B.V., 2022)
Here, we propose a novel, electrochemical preparation of in situ N-doped alginate-based carbon precursors with monodispersed zinc ions. Obtained carbons were evaluated by spectroscopic (FTIR, Raman and XPS), textural (N2 ...
Heavy metal and pesticide exposure: A mixture of potential toxicity and carcinogenicity
(Elsevier B.V., 2020)
There is a growing body of evidence that various pesticides and heavy metals are carcinogenic. If not directly, there is also evidence that shows that these compounds can participate in carcinogenesis in a passive or ...
pH-sensitive microparticles for oral drug delivery based on alginate/oligochitosan/Eudragit (R) L100-55 "sandwich" polyelectrolyte complex
(Elsevier Science BV, Amsterdam, 2013)
The primary objective of this study was to investigate the influence of the oligochitosan-Eudragit (R) L100-55 polyelectrolyte complex (OCH-EL PEC) on the pH-sensitivity of Eudragit (R) L100-55-treated alginate-oligochitosan ...
Potential Influence of Tubular Dysfunction on the Difference Between Estimated and Measured Glomerular Filtration Rate After Kidney Transplantation
(Elsevier Science Inc, New York, 2013)
Purpose. Because no consensus exists regarding the most accurate calculation to estimate glomerular filtration rate (GFR) based on serum creatinine concentrations (sCr) after kidney transplantation, this study sought to ...