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Characterization of caprylocaproyl macrogolglycerides based microemulsion drug delivery vehicles for an amphiphilic drug
(Elsevier Science BV, Amsterdam, 2004)
Microemulsion systems composed of water, isopropyl myristate, PEG-8 caprylic/captzc glycerides (Labrasol((R))), and polyglyceryl-6 dioleate (Plurol Oleique((R))), were investigated as potential drug delivery vehicles for ...
Development and validation of RP-HPLC method for cetrimonium bromide and lidocaine determination
(Elsevier Masson SAS, 2005)
The simple and rapid RP-HPLC method, for the simultaneous determination of lidocaine and cetrimonium bromide in the presence of pellet color corrigent, was developed. Separations were performed on a Beckman Ultrasphere ODS ...
Determination of all pK(a) values of some di- and tri-carboxylic unsaturated and epoxy acids and their polylinear correlation with the carboxylic group atomic charges
(Scientific Reviews Ltd., 2003)
For a series of seven unsaturated and seven epoxy di- and tricarboxylic acids, pK(a)(a) values were determined potentiometrically in aqueous media at 25 degreesC and an ionic strength of 0.1 M (NaCl). The thermodynamic ...
Ring closing metathesis/fragmentation route to (Z)-configured medium ring cycloalkenes. Total synthesis of (+/-)-periplanone C
(Amer Chemical Soc, Washington, 2006)
The combination of ring closing metathesis and beta-fragmentation offers an efficient entry into (Z)-configured medium ring cycloalkenes. The fragmentation step can be effected under anionic or radical conditions. The ...
Gonadotropin-releasing hormone agonist administration affects the thymopoiesis in adult female rats independently on gonadal hormone production
(Blackwell Munksgaard, Copenhagen, 2005)
PROBLEM: In addition to having an indirect effect on the T-cell development by controlling the production of ovarian steroids, an accumulating body of evidence suggest that GnRH analogue (GnRH-A) administration may exert ...
Multivariate characterization of herbal drugs and rhizosphere soil samples according to their metallic content
(Elsevier Science BV, Amsterdam, 2006)
Seven herbal drugs and corresponding rhizosphere soil samples from the plantation near Belgrade were analyzed for mineral content. Eleven metals (Cu, Zn, Mn, Fe, Cr, Ni, Pb, Cd, Ca, K and Mg) were selected as chemical ...
Polymer-stabilized emulsion systems: Structural characteristics and physical stability evaluation
(Taylor & Francis Ltd, Abingdon, 2003)
In the course of investigation of the effects of polymeric emulsifier (Simulgel(R)A) on the structural characteristics and physical stability (during storage time) of semisolid o/w emulsion systems with different emulsifier ...
Liquid chromatographic-mass spectrometric method for the determination of fluoxetine and norfluoxetine in human plasma: Application to clinical study
(Elsevier Masson SAS, 2005)
A selective, sensitive, simple, and rapid method for the simultaneous determination of fluoxetine (FL) and norfluoxetine (nor-FL) was developed and validated, and further applied to analyze plasma samples obtained from ...
Quantitative analysis of nimesulide in plasma by thin-layer chromatography: Application to pharmacokinetic studies in man
(Research Inst Medicinal Plants, Budakalasz, 2003)
A thin-layer chromatographic (TLC) method for quantitative analysis of nimesulide in human plasma has been developed, validated, and applied to a pharmacokinetic study of healthy volunteers. A previously published method ...
Determination of dissociation constants of quercetin
(Govi-Verlag Gmbh, Eschborn, 2003)