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Body mass index is independently associated with xanthine oxidase activity in overweight/obese population
(Springer International Publishing, 2020)
Purpose: The pathophysiological mechanism of the relationship between xanthine oxidase (XO) activity and obesity has not been completely elucidated. Since inflammation and oxidative stress are regarded as key determinants ...
Oxidative stress and renal toxicity after subacute exposure to decabrominated diphenyl ether in Wistar rats
(Springer Heidelberg, Heidelberg, 2018)
Fully brominated diphenyl ether (BDE-209) is a flame retardant widely used in plastics and textiles. Because of its high persistence, humans are exposed to it continuously, mainly via dust ingestion. We investigated effects ...
HDL 2 Particles are associated with hyperglycaemia, lower PON1 activity and oxidative stress in type 2 diabetes mellitus patients
(Pergamon-Elsevier Science Ltd, Oxford, 2010)
Objectives: In this study we examined the relationship of oxidative stress and hyperglycaemia to antioxidative capacity of high-density cholesterol (HDL-C) particles in type 2 diabetes mellitus (DM). Design and methods: ...
Protective effect of dry olive leaf extract in adrenaline induced DNA damage evaluated using in vitro comet assay with human peripheral leukocytes
(Pergamon-Elsevier Science Ltd, Oxford, 2014)
Excessive release of stress hormone adrenaline is accompanied by generation of reactive oxygen species which may cause disruption of DNA integrity leading to cancer and age-related disorders. Phenolic-rich plant product ...
Route-dependent effects of cadmium/cadmium and magnesium acute treatment on parameters of oxidative stress in rat liver
(Pergamon-Elsevier Science Ltd, Oxford, 2012)
The study was designed to evaluate and compare the effects of single oral (or) and intraperitoneal (i.p.) cadmium (Cd) administration on parameters of oxidative stress in liver of rats. Furthermore, investigation on ...
Oxidative stress, HDL and atherosclerosis
(Anti-Inflammatory and Anti-Allergy Agents in Medicinal Chemistry, 2008)
Oxidative stress is a result of an imbalanced equilibrium between reactive oxygen species (ROS) generation and their elimination by antioxidants. There is substantial evidence indicating that exacerbated oxidative stress ...
Markers of Oxidative Stress and Endothelial Dysfunction Predict Haemodialysis Patients Survival
(S. Karger AG, 2019)
Introduction: Overall survival of patients with end-stage renal disease (ESRD) remains poor. Oxidative stress is one of the major risk factors associated with mortality in this patient group. As glutathione S-transferases ...
A hazardous link between malnutrition, inflammation and oxidative stress in renal patients
(Pergamon-Elsevier Science Ltd, Oxford, 2012)
Background: Atherosclerosis is the main cause of mortality in end stage renal disease (ESRD) patients. Design and methods: Malnutrition, inflammation and diminished paraoxonase activity were used to calculate the sum of ...
The effect of inhibition of nitric oxide synthase on aluminium-induced toxicity in the rat brain
(General Physiol And Biophysics, Bratislava, 2009)
The goal of the present study was to examine the effectiveness of a non-specific nitric oxide synthase (NOS) inhibitor N-nitro-L-arginine methyl ester (L-NAME) to modulate the toxicity of aluminium chloride (AlCl3). Rats ...
Xanthine oxidase and uric acid as independent predictors of albuminuria in patients with diabetes mellitus type 2
(Springer-Verlag Italia Srl, Milan, 2018)
Xanthine oxidase (XO) is an important enzyme responsible for conversion of purine bases to uric acid and represents the major source of reactive oxygen species (ROS) production in circulation. Since pathophysiological ...