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Abyssomicins: Isolation, properties, and synthesis
(Elsevier B.V., 2013)
The discovery of abyssomicin class of natural products has been the outcome of the search for secondary metabolites possessing inhibitory effect on p-aminobenzoic (pABA) acid biosynthesis, a biosynthetic pathway found in ...
Robustness of liquid chromatographic method: How to achieve it and how to confirm it?
(Nova Science Publishers, Inc., 2013)
The quality of liquid chromatographic methods developed for pharmaceutical applications is strongly dependent on their robustness. The robustness issue requires a studious strategy where many important aspects regarding ...
Modified Natural Zeolites-Functional Characterization and Biomedical Application
(Wiley Blackwell, 2014)
Natural and synthetic zeolites have emerged as potential materials for biomedical application in recent years. Zeolites are hydrated microporous tektoaluminosilicates consisting of three-dimensional frameworks of SiO4 and ...
Objective skin performance evaluation: How mild are APGs to the skin?
(Elsevier Inc., 2014)
Emulsion systems are the most common vehicles for topical drugs/cosmetic actives. Absence of skin irritation potential is an important legislative requirement. Overcoming emulsion irritancy is usually achieved by selection ...
Quality-by-design in pharmaceutical development
(Elsevier Inc., 2013)
This first chapter introduces the concept of quality-by-design (QbD) and its role in pharmaceutical product development. QbD assures the quality of a pharmaceutical product through scientific development and risk management ...
Advanced QSRR Modeling in β-CD-Modifed RP-HPLC System
(Marcel Dekker Inc., 2023)
Percutaneous penetration enhancement potential of microemulsion-based organogels
(Springer Berlin Heidelberg, 2016)
The skin, and particularly the most outer layer stratum corneum, is an effective barrier for molecules administered by conventional topical formulations (i.e., ointments, creams, hydrogels). Therefore, vehicles and carriers ...
Alkyl Polyglucoside-based delivery systems: In vitro/in vivo skin absorption assessment
(Elsevier Inc., 2014)
Skin permeation and penetration assessment is important not only for determining efficacy of a topical product, but also when comparing different formulations during development. This chapter reviews methods for dermal ...
Polymeric Microparticles and Inorganic Micro/Nanoparticulate Drug Carriers: An Overview and Pharmaceutical Application
(Elsevier Inc., 2017)
Recent expansion of innovative micro- and nanosized drug carriers has been driven by utilization of materials with improved functional properties, along with employment of innovative preparation techniques. Various materials ...
Natural and Modified Silica-Based Materials as Carriers for NSAIDs
(Elsevier Inc., 2017)
In the last two decades several representatives of natural silica-based materials (clays, zeolites, and diatomites) have emerged in biomedical applications due to their favorable physicochemical and functionality-related ...