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Приказ резултата 31-40 од 1697
Утицај примене монаколина K на ефикасност синтезе и апсорпције холестерола / The effect of monacolin K administration on efficiency of the cholesterol synthesis and absorption
(2021)
Хиперхолестеролемија је стање које се карактерише повећаном концентрацијом укупног и LDL холестерола. Основу терапијског приступа код пацијената са хиперхолестеролемијом чине статини. Имајући у виду структуру монаколина К ...
Antiallergic Treatment of Bariatric Patients: Potentially Hampered Solubility/Dissolution and Bioavailability of Loratadine, but Not Desloratadine, Post-Bariatric Surgery
(American Chemical Society, 2022)
Gastrointestinal anatomical/physiological changes after bariatric surgery influence variables affecting the fate of drugs after ingestion, and medication management of these patients requires a thorough and complex mechanistic ...
Impact of the novel CYP2C:TG haplotype and CYP2B6 variants on sertraline exposure in a large patient population
(John Wiley and Sons Inc, 2022)
Sertraline is a commonly used SSRI antidepressant drug, metabolized by CYP2C19 and CYP2B6, that exhibits a substantial interindividual variation in clinical response, of which only a part can be attributed to known genetic ...
Influence of spray-drying process on properties of chitosan/xanthan gum polyelectrolyte complexes as carriers for oral delivery of ibuprofen / Uticaj postupka sušenja raspršivanjem na svojstva polielektrolitnih kompleksa hitozana i ksantan gume kao nosača za peroralnu isporuku ibuprofena
(Savez farmaceutskih udruženja Srbije, 2022)
Polyelectrolyte complexes (PECs) are attractive carriers with recognized potential to
enhance oral delivery of poorly soluble high-dosed low-molecular-weight drugs. The formulation
of solid oral dosage forms requires the ...
Improving tableting performance of lactose monohydrate by fluid-bed melt granulation co-processing
(MDPI, 2021)
Co-processing is commonly used approach to improve functional characteristics of pharmaceutical excipients to become suitable for tablet production by direct compression. This study aimed to improve tableting characteristics ...
Маркери синтезе и апсорпције холестерола у нефротском синдрому / Markers of cholesterol synthesis and absorption in nephrotic syndrome
(2021)
Нефротски синдром је скуп поремећаја које карактерише губитак протеина урином, што резултује протеинуријом, хипоалбуминемијом и појавом едема. У нефротском синдрому долази до малих морфолошких промена у гломерулу, што за ...
3d printed buccal films for prolonged-release of propranolol hydrochloride: Development, characterization and bioavailability prediction
(MDPI, 2021)
Gelatin-polyvinylpyrrolidone (PVP) and gelatin-poly(vinyl alcohol) (PVA) mucoadhesive buccal films loaded with propranolol hydrochloride (PRH) were prepared by semi-solid extrusion 3D printing. The aim of this study was ...
Atherosclerosis Development and Progression: The Role of Atherogenic Small, Dense LDL
(MDPI, 2022)
Atherosclerosis is responsible for large cardiovascular mortality in many countries globally. It has been shown over the last decades that the reduction of atherosclerotic progression is a critical factor for preventing ...
Detecting scaling in phase transitions on the truncated Heisenberg algebra
(Springer Science and Business Media Deutschland GmbH, 2021)
We construct and analyze a phase diagram of a self-interacting matrix field coupled to curvature of the non-commutative truncated Heisenberg space. The model reduces to the renormalizable Grosse-Wulkenhaar model in an ...
Vasodilatory effects of a variety of positive allosteric modulators of GABAA receptors on rat thoracic aorta
(Elsevier B.V., 2021)
Different subtypes of GABAA (gamma-aminobutyric acid A) receptors, through their specific regional and cellular localization, are involved in the manifestation of various functions, both at the central and peripheral levels. ...