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Design Space Approach in Optimization of Fluid Bed Granulation and Tablets Compression Process
(Hindawi Publishing Corporation, New York, 2012)
The aim of this study was to optimize fluid bed granulation and tablets compression processes using design space approach. Type of diluent, binder concentration, temperature during mixing, granulation and drying, spray ...
Novel positive allosteric modulators of GABAA receptors: Do subtle differences in activity at alpha 1 plus alpha 5 versus alpha 2 plus alpha 3 subunits account for dissimilarities in behavioral effects in rats?
(Pergamon-Elsevier Science Ltd, Oxford, 2010)
Over the last years, genetic studies have greatly improved Our knowledge on the receptor subtypes mediating various pharmacological effects of positive allosteric modulators at GABA(A) receptors. This stimulated the ...
Encapsulation and release of vitamin C in double W/O/W emulsions followed by complex coacervation in gelatin-sodium caseinate system
(Elsevier Ltd, 2021)
The objective of this study was to produce and characterize microcapsules for simultaneous encapsulation hydrophilic and lipophilic active substances. For this purpose, double emulsification process was employed, followed ...
Health risk assessment of toxic metals and toxigenic fungi in commercial herbal tea samples from Belgrade, Serbia
(Academic Press Inc., 2021)
This study aimed to: (i) determine the content of toxic metals and toxigenic fungi in 14 commercial herbal tea samples from the market of Belgrade, Serbia; and (ii) assess their risk to human health. After the microwave ...
Antibacterial and cytotoxic activities of wild mushroom Fomes fomentarius (L.) Fr., Polyporaceae
(Elsevier Science BV, Amsterdam, 2016)
The antibacterial activity of cyclohexane, dichlormethane, methanol and aqueous extracts of tinder fungus Fomes fomentarius (L) Fr (Polyporaceae) was tested against 9 bacterial strains (Staphylococcus aureus, Staphylococcus ...
Specific changes in the mammalian gut microbiome as a biomarker for oxytocin-induced behavioral changes
(MDPI, 2021)
Humans are colonized by bacteria, fungi, archaea, and viruses, which are collectively referred to as the microbiome. Most of the microbiome resides in the gut and may easily be investigated via stool sampling and subsequent ...
Massage-like stroking boosts the immune system in mice
(Nature Publishing Group, London, 2015)
Recent clinical evidence suggests that the therapeutic effect of massage involves the immune system and that this can be exploited as an adjunct therapy together with standard drug-based approaches. In this study, we ...
Estimation of passive gastrointestinal absorption and membrane retention using PAMPA test, quantitative structure-permeability and quantitative structure-retention relationship analyses of ethylenediamine-N,N'-di-2-(3-cyclohexyl)propanoic acid and 1,3-propanediamine-N,N'-di-2-(3-cyclohexyl)propanoic acid derivatives
(Elsevier B.V., 2020)
Passive gastrointestinal absorption and membrane retention of twelve esters of (S,S)-ethylenediamine-N,N'-di-2-(3-cyclohexyl)propanoic acid (EDCP) and (S,S)-1,3-propanediamine-N,N'-di-2-(3-cyclohexyl)propanoic acid (PDCP), ...
Self-reported perinatal depressive symptoms and postnatal symptom severity after treatment with antidepressants in pregnancy: a cross-sectional study across 12 European countries using the Edinburgh Postnatal Depression Scale
(Dove Medical Press Ltd, Albany, 2018)
Purpose: This study aimed at exploring the prevalence of self-reported antenatal and postnatal depressive symptoms by severity across multiple countries and the association between antidepressant treatment in pregnancy and ...
Effects of α5 GABAA receptor modulation on social interaction, memory, and neuroinflammation in a mouse model of Alzheimer's disease
(John Wiley and Sons Inc, 2022)
Aims: GABAergic modulation involved in cognitive processing appears to be substan- tially changed in Alzheimer's disease (AD). In a widely used 5xFAD model of AD, we aimed to assess if negative and positive allosteric ...