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Toward the synthesis of incargranine B and seneciobipyrrolidine. Synthesis of octahydro-dipyrroloquinoline skeleton via dipolar cycloaddition/amination sequence
(Wiley, HeteroCorporation, 2021)
Octahydro-dipyrroloquinoline skeleton is the building component of a very few naturally occurring compounds. Nevertheless, these natural products have been attractive synthetic targets, and their study commanded development ...
3d printed buccal films for prolonged-release of propranolol hydrochloride: Development, characterization and bioavailability prediction
(MDPI, 2021)
Gelatin-polyvinylpyrrolidone (PVP) and gelatin-poly(vinyl alcohol) (PVA) mucoadhesive buccal films loaded with propranolol hydrochloride (PRH) were prepared by semi-solid extrusion 3D printing. The aim of this study was ...
Detecting scaling in phase transitions on the truncated Heisenberg algebra
(Springer Science and Business Media Deutschland GmbH, 2021)
We construct and analyze a phase diagram of a self-interacting matrix field coupled to curvature of the non-commutative truncated Heisenberg space. The model reduces to the renormalizable Grosse-Wulkenhaar model in an ...
The impact of treatment choices on potential drug–drug interactions in hypertensive patients
(John Wiley and Sons Inc, 2021)
Aims: The aim of this study was to analyse potential drug–drug interactions (pDDIs) and their potential adverse drug reactions (ADRs) among hypertensive patients. Moreover, we investigated the possibility of reducing pDDIs ...
Anthropometric, strength, endurance and flexibility characteristics of male elite ice climbers and sport climbers / Anthropometrische, kraft-, ausdauer-und flexibilitätsmerkmale männlicher elite-eiskletterer und sportkletterer
(Dynamic Media Sales Verlag, 2021)
Objective: Purpose of this study was to compare elite male ice climbers and sport climbers for their anthropometry, muscular strength, endurance, and flexibility. Although there is a certain overlap between these two ...
Development of lipid-based gastroretentive delivery system for gentian extract by double emulsion–melt dispersion technique
(MDPI, 2021)
Gentian (Gentiana lutea L., Gentianaceae) root extract (GRE) is used for the treatment of gastrointestinal disorders. However, its bioactive potential is limited in conventional forms due to the low bioavailability and ...
Revealing the role of high-density lipoprotein in colorectal cancer
(MDPI AG, 2021)
Colorectal cancer (CRC) is a highly prevalent malignancy with multifactorial etiology,which includes metabolic alterations as contributors to disease development. Studies have shownthat lipid status disorders are involved ...
Study of chitosan/xanthan gum polyelectrolyte complexes formation, solid state and influence on ibuprofen release kinetics
(Elsevier B.V., 2020)
This study investigated the combined influence of pH adjusting agent type (hydrochloric, acetic or lactic acid) and initial pH value (3.6, 4.6, and 5.6) on formation of biocompatible chitosan/xanthan polyelectrolyte complexes ...
Binuclear Co(II) complexes with macrocycle and carboxylato ligands: structure, cytotoxicity and thermal behavior
(Elsevier B.V., 2021)
In vitro cytotoxic evaluation, formation constants and thermal stability of four mixed-ligand Co(II) complexes with tpmc = N,N',N",N'"-tetrakis(2-pyridylmethyl)-1,4,8,11-tetraazacyclotetradecane and carboxylate/dicarboxylate ...
Protective effects of fruit wines against hydrogen peroxide—induced oxidative stress in rat synaptosomes
(MDPI AG, 2021)
This study aimed to evaluate, in vitro, the antioxidative potential of fruit wines produced from berry fruits (i.e., black chokeberry, blueberry, blackberry, and raspberry), cherry, and apple by different technological ...