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Prikaz rezultata 1-10 od 55
Inhibitors of tumor necrosis factor-α and mechanisms of their action / Inhibitori faktora nekroze tumora–α i mehanizmi njihovog dejstva
(Beograd : Savez farmaceutskih udruženja Srbije, 2020)
Tumor necrosis factor (TNF)-α is a proinflammatory cytokine with a role in immunity to pathogens, as well as in the pathogenesis of several autoimmune/inflammatory diseases. Biological drugs targeting this cytokine and ...
Chaotropic effect of trifluoroacetic and perchloric acid on β-cyclodextrininclusion complexation process with risperidone, olanzapine and their selected impuritiesN / Haotropni efekat trifluorosirćetne i perhlorne kiseline na formiranje inkluzionih kompleksa između β-ciklodekstrina irisperidona, olanzapinainjihovih srodnih supstanci
(Beograd: Savez farmaceutskih udruženja Srbije, 2020)
Effective method development together with method`s eco-friendly character are gaining importance in drug analyses nowadays. One of the strategies often applied to improve the efficacy of separation methods, especially in ...
Direct oral anticoagulants – a new chapter in anticoagulation therapy / Direktni oralni antikoagulansi - novo poglavlje u antikoagulantnoj terapiji
(Beograd : Savez farmaceutskih udruženja Srbije, 2020)
Thromboembolic events are the leading cause of morbidity and mortality worldwide. From the second half of the 20th century, vitamin K antagonists (VKAs), warfarin and acenocoumarol, were the only anticoagulants taken orally. ...
Chemometric window to antimicrobial activity of biomolecules isolated from endophytic fungi / Hemometrijski prozor ka antibakterijskoj aktivnosti biomolekula izolovanih iz endofitnih gljiva
(Pharmaceutical Association of Serbia, 2020)
Drug resistance, especially bacterial antibiotic resistance, is recognized as a global phenomenon. Potential of endophytic fungi as producers of secondary metabolites with wide spectra of different bioactivities in the ...
The current place of direct oral anticoagulants in the prevention/treatment of venous thromboembolism / Mesto direktnih oralnih antikoagulansa u prevenciji/lečenju venskog tromboembolizma
(Beograd : Savez farmaceutskih udruženja Srbije, 2020)
Venous thromboembolism (VTE; includes deep venous thrombosis, DVT, and pulmonary embolism, PE) represents the third most common acute cardiovascular syndrome. Contemporary VTE management comprises primary prevention in ...
The emerging role of physiologically-based pharmacokinetic/biopharmaceutics modeling in formulation development / Uloga fiziološki-zasnovanog farmakokinetičkog/biofarmaceutskog modelovanja u razvoju farmaceutskih preparata
(Beograd : Savez farmaceutskih udruženja Srbije, 2021)
Computer-based (in silico) modeling & simulation tools have been embraced in different
fields of pharmaceutics for a variety of applications. Among these, physiologically-based
pharmacokinetic/biopharmaceutics modeling ...
Experimental design in HPLC separation of pharmaceuticals / Primena eksperimentalnog dizajna za razdvajanje lekova HPLC metodom
(Beograd : Savez farmaceutskih udruženja Srbije, 2021)
Design of Experiments (DoE) is an indispensable tool in contemporary drug analysis as it
simultaneously balances a number of chromatographic parameters to ensure optimal separation
in High Pressure Liquid Chromatography ...
Current computer-aided drug design methodologies in discovery of novel drug candidates for neuropsychiatric and inflammatory diseases / Metode kompjuterski potpomognutog dizajniranja lekova u istraživanju novih potencijalnih terapeutika za neuropsihijatrijske i inflamatorne bolesti
(Beograd : Savez farmaceutskih udruženja Srbije, 2021)
Drug discovery and development is a very challenging, expensive and time-consuming
process. Impressive technological advances in computer sciences and molecular biology have
made it possible to use computer-aided drug ...
Relevance and evaluation of the benchmark dose in toxicology / Značaj i procena benchmark doze u toksikologiji
(Beograd : Savez farmaceutskih udruženja Srbije, 2020)
This paper aims to present the importance of the benchmark dose (BMD) as a point of departure (the lowest dose or concentration in the experiment that deviates from the response that differs from the normal ...
Modelling in economic evaluations of medicines / Modelovanje u farmakoekonomskim evaluacijama lekova
(Beograd : Savez farmaceutskih udruženja Srbije, 2021)
Economic evaluation in health (also known as pharmacoeconomic in case of medicines)
identifies, measures, and values costs and outcomes of alternative healthcare technologies, and
can be performed alongside controlled ...