Pretraživanje
Prikaz rezultata 1-10 od 131
Effect of small changes in natural origin-based emulsion systems on hydrocortisone skin absorption and performance: a comparison of two in vivo methods
(Taylor & Francis Ltd, Abingdon, 2014)
Context: Alkyl polyglucoside surfactants (APG) remain prominent natural origin stabilizers offering a prospect of combining satisfactory stability with mild dermatological properties and complete biodegradability. Objective: ...
Synthesis, characterization and antimicrobial activity of Pd(II) and Fe(III) complexes with ethyl (2E)-2-[2-(diphenylphosphino)benzylidene]hydrazinecarboxylate
(Pergamon-Elsevier Science Ltd, Oxford, 2014)
Complexes of Pd(II) and Fe(III) with the condensation derivative of 2-(diphenylphosphino)benzaldehyde and ethyl carbazate were synthesized, characterized, and their antimicrobial activity was evaluated. The structures of ...
Subacute toxicity of PCBs in rats: Is hepatic oxidative stress induction dose dependent?
(Elsevier Ireland Ltd, Clare, 2014)
Are antidepressants effective in quality of life improvement among children and adolescents? A systematic review
(Cambridge University Press, 2014)
There is some evidence indicating that psychotropic medications might lead to health-related quality of life (QOL) improvements among children and adolescents with psychiatric disorders. The aim of this systematic review ...
Sucrose ester-based biocompatible microemulsions as vehicles for aceclofenac as a model drug: formulation approach using D-optimal mixture design
(Springer, New York, 2014)
We assessed the functionality of sucrose esters (sucrose laurate, myristate, palmitate, and stearate), relatively innocuous nonionic surfactants, in formulation of biocompatible microemulsions. The putative influence of ...
Identifying the CmbT substrates specificity by using a quantitative structure-activity relationship (QSAR) study
(Elsevier Science BV, Amsterdam, 2014)
The CmbT substrate specificity and its role as a proton motive force-driven drug efflux pump at a molecular level were investigated in the study. In that order, 3D-quantitative structure-activity relationship (3D-QSAR) ...
Phenolic profile, antibacterial, antimutagenic and antitumour evaluation of Veronica urticifolia Jacq.
(Elsevier Science BV, Amsterdam, 2014)
The phenolic profile and antibacterial, antimutagenic and antitumour activities of the methanolic extracts of Veronica urticifolia Jacq. were evaluated. HPLC-DAD/ESI-MS analysis revealed the presence of phenolic acids, ...
Organocatalysis in Synthesis of Pyrrolidine Derivatives via Cycloaddition Reactions of Azomethine Ylides
(Bentham Science Publ Ltd, Sharjah, 2014)
Cycloaddition reactions of azomethine ylides are the most direct way to synthesise pyrrolidine derivatives. They have been studied for several decades and have become an indispensable tool in synthesis of pyrrolidines and ...
Pharmacokinetics of lamotrigine in paediatric and young adult epileptic patients-nonlinear mixed effects modelling approach
(Springer Heidelberg, Heidelberg, 2014)
The purpose of the study was to examine and describe adjunctive lamotrigine (LTG) pharmacokinetics in paediatric and young adult patients using a nonlinear mixed effects modelling (NONMEM) approach. The study included 53 ...
No effect of carbamazepine daily dose on phenobarbital elimination in adult epileptic patients - population pharmacokinetic analysis
(Elsevier Science BV, Amsterdam, 2014)