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Uticaj micela različitog naelektrisanja kao simulirajućih sistema biomembrana na jonizaciju rupatadina / The effects of differently charged micelles as biomembrane mimetic systems on the ionization of rupatadine
(Savez farmaceutskih udruženja Srbije (SFUS), 2018)
Rupatadin je selektivni antagonist histaminskih H1 receptora druge generacije
koji se primenjuje u terapiji alergijskog rinitisa i hronične urtikarije. Rupatadin sadrži
tri jonizaciona centra, dva aromatična amina i jedan ...
Potentiometric determination of pKa values of ACE inhibitors
(Serbian Chemical Society, 2013)
ACE (angiotensin-converting enzyme) inhibitors are drugs applied in the treatment of
different cardiovascular disorders, primarily in the therapy of hypertension and congestive
cardial insufficiency. The presence of ...
The effects of anoinic and cationic surfactants on acid-base equilibria of irbesartan
(Society of Physical Chemists of Serbia, 2014)
In this study the pKa values of irbesartan, an angiotensin receptor blocker, were
determined by potentiometry and the effects of sodium dodecyl sulfate
(SDS) and cetyl trimethyl ammonium bromide (CTAB) on its ...
The effects of micellar solutions of surfactants on protolytic equilibria of ACE inhibitors / Uticaj micelarnih rastvora surfaktanata na protolitičke ravnoteže ACE inhibitora
(Savez farmaceutskih udruženja Srbije, 2014)
ACE inhibitors are drugs applied in the treatment of different cardiovascular disorders.
Because to the presence of carboxyl, thiol, primary and secondary amino ionizable groups
these compounds represent acids and ...
Acid-base equilibria and solubility of verapamil
(Society of Physical Chemists of Serbia, 2016)
The intrinsic solubility – S0 (only the neutral form is present in the solution)
and pH-dependent solubility - S (heterogeneous system of neutral and
ionized forms) of verapamil were determined spectrophotometrically. ...