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Now showing items 11-20 of 1033
Synthesis and characterization of copper(II) octaazamacrocyclic complexes with glycine derivatives. In vitro antiproliferative and antimicrobial evaluation of the Cu(II) and Co(II) analogous
(Belgrade : Serbian Chemical Society, 2020)
Two new complexes with the general formula [Cu2(L)tpmc](ClO4)3·nH2O (tpmc = N,N′,N′′,N′′′-tetrakis(2-pyridylmethyl)- -1,4,8,11-tetraazacyclotetradecane, L = N-methylglycine, n = 3; L = N,N- -dimethylglycine, ...
Shotgun metagenomics reveals differences in antibiotic resistance genes among bacterial communities in Western Balkans glacial lakes sediments
(NLM (Medline), 2020)
Long-term overuse of antibiotics has driven the propagation and spreading of antibiotic resistance genes (ARGs) such as efflux pumps in the environment, which can be transferred to clinically relevant pathogens. This study ...
ACTH, Cortisol and IL-6 Levels in Athletes Following Magnesium Supplementation
(Društvo medicinskih biohemičara Srbije, Beograd i Versita, 2016)
Background: Physical exercise activates the hypothalamopituitary-adrenal (HPA) axis and induces the body's inflammatory response. Due to contemporary dietary habits and increased energy expenditure, athletes are susceptible ...
Influence of Promoter Polymorphisms of the Tnf-α (-308g/A) and IL-6 (-174g/C) Genes on Therapeutic Response to Etanercept in Rheumatoid Arthritis
(Društvo medicinskih biohemičara Srbije, Beograd i Versita, 2015)
Background: The study was undertaken to assess the influence of functional -308G/A TNF-alpha (rs 1800629) and -174G/C IL-6 (rs1800795) promoter polymorphisms on the therapeutic response to etanercept, a TNF-alpha. blocker, ...
Spectroscopic studies on the drug–drug interaction: the influence of fluoroquinolones on the affinity of tigecycline to human serum albumin and identification of the binding site
(Springer, 2020)
bstract: Concomitant use of two or more drugs in therapy is becoming a more frequent phenomenon and clinically relevant drug–drug interactions at the level of binding to human serum albumin (HSA) are more often. The influence ...
Apolipoprotein E polymorphism and severity of angiographically verified coronary artery disease
(Društvo medicinskih biohemičara Srbije i Crne Gore, Beograd i Univerzitet u Beogradu - Farmaceutski fakultet, Beograd, 1999)
Apolipoprotein E is an important genetic determinant of serum lipoprotein concentrations and coronary artery disease risk. The apo E polymorphism is a major determinant of interindividual variation in the initiation and ...
Influence of ribavirin on the micronucleus formation and in vitro proliferation of human lymphocytes
(Slovak Academic Press Ltd, Bratislava, 2000)
Cytotoxic effects of the antiviremic drug ribavirin (1-beta -D-ribofuranosyl-1,2,4-triazole-3-carboxamide) were evaluated in vitro measuring micronucleus formation and cell proliferation kinetics in whole blood cultures ...
Feedback of Individual Genetic Results to Research Participants: Is It Feasible in Europe?
(Mary Ann Liebert, Inc, New Rochelle, 2016)
Background: There is growing consensus that individual genetic research results that are scientifically robust, analytically valid, and clinically actionable should be offered to research participants. However, the general ...
Protective role of maternal P.VAL158MET catechol-o-methyltransferase polymorphism against early-onset preeclampsia and its complications
(Društvo medicinskih biohemičara Srbije, Beograd i Versita, 2016)
Background: Up until now there have been contradictory data about the association between p.Val158Met catechol-O-methyltransferase (COMT) polymorphism and risk of preeclampsia (PE). The goal of this study was to assess the ...
Combined effects of cadmium and decabrominated diphenyl ether on thyroid hormones in rats
(Inst Medical Research & Occupational Health, Zagreb, 2012)
The aim of this study was to see how a mixture of cadmium (Cd) and decabrominated diphenyl ether (BDE209) affect thyroid function, namely thyroid-stimulating hormone (TSH), thyroxin (T4), free thyroxin (FT4), triiodothyronin ...