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Synthesis, characterization and antimicrobial activity of Pd(II) and Fe(III) complexes with ethyl (2E)-2-[2-(diphenylphosphino)benzylidene]hydrazinecarboxylate
(Pergamon-Elsevier Science Ltd, Oxford, 2014)
Complexes of Pd(II) and Fe(III) with the condensation derivative of 2-(diphenylphosphino)benzaldehyde and ethyl carbazate were synthesized, characterized, and their antimicrobial activity was evaluated. The structures of ...
In vivo toxicity evaluation of two polyoxotungstates with potential antidiabetic activity using Wistar rats as a model system
(Royal Society of Chemistry, 2020)
In this study, thein vivohypoglycemic effect of a donut-shaped polyanion salt (NH4)14[Na@P5W30O110]$31H2O{NaP5W30} and its Ag-containing derivative K14[Ag@P5W30O110]$22H2O$6KCl {AgP5W30}, as wellas their hepatotoxicity ...
Compensatory Neuroprotective Response of Thioredoxin Reductase against Oxidative-Nitrosative Stress Induced by Experimental Autoimmune Encephalomyelitis in Rats: Modulation by Theta Burst Stimulation
(MDPI, 2020)
Cortical theta burst stimulation (TBS) structured as intermittent (iTBS) and continuous (cTBS)could prevent the progression of the experimental autoimmune encephalomyelitis (EAE). The interplayof brain antioxidant defense ...
Olive Leaf Extract Attenuates Inflammatory Activation and DNA Damage in Human Arterial Endothelial Cells
(Frontiers Media Sa, Lausanne, 2019)
Olive leaf extract (OLE) is used in traditional medicine as a food supplement and as an over-the-counter drug for a variety of its effects, including anti-inflammatory and anti-atherosclerotic ones. Mechanisms through which ...
Simulataneous determination of nimesulide and its impurities in pharmaceutical formulations by reversed-phase high-performance liquid chromatography
(Slovensko Kemijsko Drustvo, Ljubljana, 2007)
A simple, rapid and reproducible reversed-phase high-performance liquid chromatography method for the analysis of nimesulide and its impurities both in the bulk drug and pharmaceutical formulations is reported. The method ...
From experimental design to quality by design in pharmaceutical legislation
(Springer, New York, 2012)
Quality by design (QbD) is a concept first outlined by Juran, who believed that quality could be planned and that most quality crises and problems relate to the way in which quality was planned in the first place. Experimental ...
An Investigation into the Influence of Process Parameters and Formulation Variables on Compaction Properties of Liquisolid Systems
(Springer, 2020)
Liquisolid technology, as a promising approach for bioavailability enhancement, has received increasing attention in recent years. However, literature reports addressing the challenges for its industrial application, ...
The prevalence and preventability of potentially relevant drug-drug interactions in patients admitted for cardiovascular diseases: A cross-sectional study
(Wiley, Hoboken, 2017)
Aim: The aim was to describe the type and prevalence of potentially relevant drug-drug interactions (pDDIs) in a population of patients admitted for cardiovascular diseases (CVD), and management strategies for reducing the ...
The role of rat Crry, a complement regulatory protein, in proliferation of thymocytes
(Pergamon-Elsevier Science Ltd, Oxford, 2004)
In our previous work we showed that 3F10 monoclonal antibody (mAb), which recognizes the rat complement receptor 1-related/gene protein y (Crry), induces homotipic aggregation of thymocytes. In this work we studied the ...
Imidazoline Antihypertensive Drugs: Selective I1-Imidazoline Receptors Activation
(Wiley, Hoboken, 2012)
Involvement of imidazoline receptors (IR) in the regulation of vasomotor tone as well as in the mechanism of action of some centrally acting antihypertensives has received tremendous attention. To date, pharmacological ...