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Neural computing in pharmaceutical products and process development
(Elsevier Inc., 2013)
This chapter presents a review of the possible applications of methods based on neural computing in pharmaceutical products and process development. Some of the methods described are used for classification purposes, whereas ...
Computer-aided biopharmaceutical characterization: Gastrointestinal absorption simulation
(Elsevier Inc., 2013)
This chapter introduces the concept of gastrointestinal absorption simulation using in silico methodology. Parameters used for model construction and the sensitivity predicted pharmacokinetic responses to various input ...
Natural and Modified Silica-Based Materials as Carriers for NSAIDs
(Elsevier Inc., 2017)
In the last two decades several representatives of natural silica-based materials (clays, zeolites, and diatomites) have emerged in biomedical applications due to their favorable physicochemical and functionality-related ...
Percutaneous penetration enhancement potential of microemulsion-based organogels
(Springer Berlin Heidelberg, 2016)
The skin, and particularly the most outer layer stratum corneum, is an effective barrier for molecules administered by conventional topical formulations (i.e., ointments, creams, hydrogels). Therefore, vehicles and carriers ...
Alkyl Polyglucoside-based delivery systems: In vitro/in vivo skin absorption assessment
(Elsevier Inc., 2014)
Skin permeation and penetration assessment is important not only for determining efficacy of a topical product, but also when comparing different formulations during development. This chapter reviews methods for dermal ...
Diversity and Functionality of Excipients for Micro/Nanosized Drug Carriers
(Elsevier Inc., 2017)
Continuous efforts to improve performance of drugs via incorporation in particulate and soft colloidal carriers have introduced new functional categories of excipients. These excipients are used to protect drugs, modify ...
Influence of Polycation Functional Properties on Polyanion Micro/Nanoparticles for NSAIDs Reinforced via Polyelectrolyte Complexation: Alginate-Chitosan Case Study
(Elsevier Inc., 2017)
In the last 2 decades, numerous studies have been carried out to synthesize biodegradable and nontoxic micro- and nanoparticulate carriers for nonsteroidal anti-inflammatory drugs. The potential benefits of these carriers ...
Ibuprofen delivery: Pharmaceutical nanotechnology approach
(Nova Science Publishers, Inc., 2013)
Ibuprofen is non-steroidal anti-inflammatory drug (NSAID) widely used for the treatment of pain and inflammation related with rheumatoid arthritis, osteoarthritis, dysmenorrhea, headaches, muscle pain, common cold, after ...
Experimental design application interpretation in pharmaceutical technology
(Elsevier Inc., 2013)
This chapter provides a basic theoretical background on experimental design application and interpretation. Techniques described include screening designs, full and fractional factorial designs, Plackett-Burman design, ...
Application of artificial neural networks (ANNS) in development of pharmaceutical microemulsions
(Nova Science Publishers, Inc., 2011)