Biochemical evaluation of patients with acute pancreatitis
Samo za registrovane korisnike
2000
Članak u časopisu (Objavljena verzija)
Metapodaci
Prikaz svih podataka o dokumentuApstrakt
In this study we determined the clinical accuracy of alpha (2)-macroglobulin, alpha -amylase, C-reactive protein, lipase, non-esterified fatty acids, pancreatic alpha -amylase and phospholipase A in the diagnosis and prognosis of acute pancreatitis in a group of patients with acute abdominal pain using receiver operator characteristic curve analysis. We investigated 59 patients with acute pancreatitis and 72 patients with extrapancreatic diseases of gastrointestinal origin. On the basis of initial enzyme activities, at cut-offs of 245 U/I for amylase. 656 U/I for lipase, and 182 U/I for pancreatic alpha -amylase, the diagnostic efficiencies were 0.993, 0.980, and 0.975, respectively. Receiver operator characteristic curve analysis showed the same diagnostic accuracies. We evaluated the accuracy of serum alpha (2)-macroglobulin, C-reactive protein, non-esterified fatty acids end phospholipase A for differentiation between acute necrotizing pancreatitis and acute oedematous pancreatitis.... C-reactive protein had the highest prognostic accuracy of the parameters studied (the area under curve = 0.9082) and at a cut-off value of 126 mg/l, sensitivity and specificity were 0.759 and 0.912, respectively. The role of the clinical laboratory in the investigation of patients with acute pancreatitis continues to evolve and biochemical parameters are a good diagnostic and prognostic: option.
Izvor:
Clinical Chemistry and Laboratory Medicine, 2000, 38, 11, 1141-1144Izdavač:
- Walter de Gruyter & Co, Berlin
DOI: 10.1515/CCLM.2000.173
ISSN: 1434-6621
PubMed: 11156345
WoS: 000166596600014
Scopus: 2-s2.0-0034521239
Institucija/grupa
PharmacyTY - JOUR AU - Ignjatović, Svetlana AU - Majkić-Singh, Nada AU - Mitrović, M. AU - Gvozdenović, Miomir PY - 2000 UR - https://farfar.pharmacy.bg.ac.rs/handle/123456789/241 AB - In this study we determined the clinical accuracy of alpha (2)-macroglobulin, alpha -amylase, C-reactive protein, lipase, non-esterified fatty acids, pancreatic alpha -amylase and phospholipase A in the diagnosis and prognosis of acute pancreatitis in a group of patients with acute abdominal pain using receiver operator characteristic curve analysis. We investigated 59 patients with acute pancreatitis and 72 patients with extrapancreatic diseases of gastrointestinal origin. On the basis of initial enzyme activities, at cut-offs of 245 U/I for amylase. 656 U/I for lipase, and 182 U/I for pancreatic alpha -amylase, the diagnostic efficiencies were 0.993, 0.980, and 0.975, respectively. Receiver operator characteristic curve analysis showed the same diagnostic accuracies. We evaluated the accuracy of serum alpha (2)-macroglobulin, C-reactive protein, non-esterified fatty acids end phospholipase A for differentiation between acute necrotizing pancreatitis and acute oedematous pancreatitis. C-reactive protein had the highest prognostic accuracy of the parameters studied (the area under curve = 0.9082) and at a cut-off value of 126 mg/l, sensitivity and specificity were 0.759 and 0.912, respectively. The role of the clinical laboratory in the investigation of patients with acute pancreatitis continues to evolve and biochemical parameters are a good diagnostic and prognostic: option. PB - Walter de Gruyter & Co, Berlin T2 - Clinical Chemistry and Laboratory Medicine T1 - Biochemical evaluation of patients with acute pancreatitis VL - 38 IS - 11 SP - 1141 EP - 1144 DO - 10.1515/CCLM.2000.173 ER -
@article{ author = "Ignjatović, Svetlana and Majkić-Singh, Nada and Mitrović, M. and Gvozdenović, Miomir", year = "2000", abstract = "In this study we determined the clinical accuracy of alpha (2)-macroglobulin, alpha -amylase, C-reactive protein, lipase, non-esterified fatty acids, pancreatic alpha -amylase and phospholipase A in the diagnosis and prognosis of acute pancreatitis in a group of patients with acute abdominal pain using receiver operator characteristic curve analysis. We investigated 59 patients with acute pancreatitis and 72 patients with extrapancreatic diseases of gastrointestinal origin. On the basis of initial enzyme activities, at cut-offs of 245 U/I for amylase. 656 U/I for lipase, and 182 U/I for pancreatic alpha -amylase, the diagnostic efficiencies were 0.993, 0.980, and 0.975, respectively. Receiver operator characteristic curve analysis showed the same diagnostic accuracies. We evaluated the accuracy of serum alpha (2)-macroglobulin, C-reactive protein, non-esterified fatty acids end phospholipase A for differentiation between acute necrotizing pancreatitis and acute oedematous pancreatitis. C-reactive protein had the highest prognostic accuracy of the parameters studied (the area under curve = 0.9082) and at a cut-off value of 126 mg/l, sensitivity and specificity were 0.759 and 0.912, respectively. The role of the clinical laboratory in the investigation of patients with acute pancreatitis continues to evolve and biochemical parameters are a good diagnostic and prognostic: option.", publisher = "Walter de Gruyter & Co, Berlin", journal = "Clinical Chemistry and Laboratory Medicine", title = "Biochemical evaluation of patients with acute pancreatitis", volume = "38", number = "11", pages = "1141-1144", doi = "10.1515/CCLM.2000.173" }
Ignjatović, S., Majkić-Singh, N., Mitrović, M.,& Gvozdenović, M.. (2000). Biochemical evaluation of patients with acute pancreatitis. in Clinical Chemistry and Laboratory Medicine Walter de Gruyter & Co, Berlin., 38(11), 1141-1144. https://doi.org/10.1515/CCLM.2000.173
Ignjatović S, Majkić-Singh N, Mitrović M, Gvozdenović M. Biochemical evaluation of patients with acute pancreatitis. in Clinical Chemistry and Laboratory Medicine. 2000;38(11):1141-1144. doi:10.1515/CCLM.2000.173 .
Ignjatović, Svetlana, Majkić-Singh, Nada, Mitrović, M., Gvozdenović, Miomir, "Biochemical evaluation of patients with acute pancreatitis" in Clinical Chemistry and Laboratory Medicine, 38, no. 11 (2000):1141-1144, https://doi.org/10.1515/CCLM.2000.173 . .