dc.description.abstract | The WHO developed the many indicators to evaluated
the rational use of drug, as following: availability of drug,
cost of drug therapy, drug cost of antibiotics in ratio of
all drug cost etc. OBJECTIVES: The purpose of research
was to analysed the antibiotic use in primary health care
of part of Republic of Srpska (RS) with commonly and
complementary indicators. METHODS: A retrospective
analysis of prescribing of antibiotic in setting of data
centre of Rp evaluation of Community Pharmacy chain
of Banja Luka (BL)(RS), was conducting using the 1990,
1994, 1998 and 2000 survey. The analysis covered the
four main group of antibiotics by indicators: defined daily
dosage (DDD)/1000 inhabitants/days; % of antibiotics
and cost vs. all drugs. The comparison was done with
survey of “reference case” in Serbia and Montenegro (SM) and Clinical-hospital centre of BL (ChcBL). Fischer
test and SD statistical method was used and multivariate
analyses, as well. RESULTS: The study included the 17
retail pharmacy settled in area of BL with the total pop-
ulation of ~350,000 people. The average use of antibiotic
is 42% (32%, 60%, 37%, 40%, respectively to time
frames) and higher than the use in SM (33%) and similar
to use in ChcBL. The structural analysis were show that
the penicillin’s and cephalosporin’s was the two main pre-
scribing antibiotic group. In deep multivariate analyses
we were recognised the radically changes in prescribes
practices after the year 2000 (increasing use of amoxi-
cillin and combination, instead of ampicillin). The in ser-
vices training of health workers (PHARE program) and
the inclusion of combination in the local reimburse-
ment list have had important role on the former results.
CONCLUSIONS: Complementary indicators of use of
antibiotics in the primary health care systems of BL
showed that the rational antibiotic use approach was
present, after strong drug policy were developed and
implemented. | |